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Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice.
Brunt VE, Greenberg NT, Sapinsley ZJ, Casso AG, Richey JJ, VanDongen NS, Gioscia-Ryan RA, Ziemba BP, Neilson AP, Davy KP, Seals DR. Brunt VE, et al. J Appl Physiol (1985). 2022 Oct 1;133(4):798-813. doi: 10.1152/japplphysiol.00350.2022. Epub 2022 Aug 11. J Appl Physiol (1985). 2022. PMID: 35952350 Free PMC article.
Keynote lecture: strategies for optimal cardiovascular aging.
Seals DR, Brunt VE, Rossman MJ. Seals DR, et al. Among authors: brunt ve. Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H183-H188. doi: 10.1152/ajpheart.00734.2017. Epub 2018 Apr 13. Am J Physiol Heart Circ Physiol. 2018. PMID: 29652545 Free PMC article.
Short-term interleukin-37 treatment improves vascular endothelial function, endurance exercise capacity, and whole-body glucose metabolism in old mice.
Ballak DB, Brunt VE, Sapinsley ZJ, Ziemba BP, Richey JJ, Zigler MC, Johnson LC, Gioscia-Ryan RA, Culp-Hill R, Eisenmesser EZ, D'Alessandro A, Dinarello CA, Seals DR. Ballak DB, et al. Among authors: brunt ve. Aging Cell. 2020 Jan;19(1):e13074. doi: 10.1111/acel.13074. Epub 2019 Nov 21. Aging Cell. 2020. PMID: 31755162 Free PMC article.
Tumor Necrosis Factor Alpha-Mediated Inflammation and Remodeling of the Extracellular Matrix Underlies Aortic Stiffening Induced by the Common Chemotherapeutic Agent Doxorubicin.
Clayton ZS, Brunt VE, Hutton DA, Casso AG, Ziemba BP, Melov S, Campisi J, Seals DR. Clayton ZS, et al. Among authors: brunt ve. Hypertension. 2021 May 5;77(5):1581-1590. doi: 10.1161/HYPERTENSIONAHA.120.16759. Epub 2021 Mar 15. Hypertension. 2021. PMID: 33719511 Free PMC article.
49 results