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Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics.
Slattery SS, Giguere DJ, Stuckless EE, Shrestha A, Briere LK, Galbraith A, Reaume S, Boyko X, Say HH, Browne TS, Frederick MI, Lant JT, Heinemann IU, O'Donoghue P, Dsouza L, Martin S, Howard P, Jedeszko C, Ali K, Styba G, Flatley M, Karas BJ, Gloor GB, Edgell DR. Slattery SS, et al. Sci Rep. 2022 Apr 29;12(1):7010. doi: 10.1038/s41598-022-11053-7. Sci Rep. 2022. PMID: 35487958 Free PMC article.
tRNAHis-guanylyltransferase establishes tRNAHis identity.
Heinemann IU, Nakamura A, O'Donoghue P, Eiler D, Söll D. Heinemann IU, et al. Nucleic Acids Res. 2012 Jan;40(1):333-44. doi: 10.1093/nar/gkr696. Epub 2011 Sep 2. Nucleic Acids Res. 2012. PMID: 21890903 Free PMC article.
Carbon source-dependent expansion of the genetic code in bacteria.
Prat L, Heinemann IU, Aerni HR, Rinehart J, O'Donoghue P, Söll D. Prat L, et al. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21070-5. doi: 10.1073/pnas.1218613110. Epub 2012 Nov 26. Proc Natl Acad Sci U S A. 2012. PMID: 23185002 Free PMC article.
Reducing the genetic code induces massive rearrangement of the proteome.
O'Donoghue P, Prat L, Kucklick M, Schäfer JG, Riedel K, Rinehart J, Söll D, Heinemann IU. O'Donoghue P, et al. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17206-11. doi: 10.1073/pnas.1420193111. Epub 2014 Nov 17. Proc Natl Acad Sci U S A. 2014. PMID: 25404328 Free PMC article.
Visualizing tRNA-dependent mistranslation in human cells.
Lant JT, Berg MD, Sze DHW, Hoffman KS, Akinpelu IC, Turk MA, Heinemann IU, Duennwald ML, Brandl CJ, O'Donoghue P. Lant JT, et al. RNA Biol. 2018;15(4-5):567-575. doi: 10.1080/15476286.2017.1379645. Epub 2017 Nov 9. RNA Biol. 2018. PMID: 28933646 Free PMC article.
Biochemistry of Synthetic Biology - Recent Developments.
O'Donoghue P, Heinemann IU. O'Donoghue P, et al. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):2945-2947. doi: 10.1016/j.bbagen.2017.10.010. Biochim Biophys Acta Gen Subj. 2017. PMID: 29107315 No abstract available.
Synthetic DNA and RNA Programming.
O'Donoghue P, Heinemann IU. O'Donoghue P, et al. Genes (Basel). 2019 Jul 11;10(7):523. doi: 10.3390/genes10070523. Genes (Basel). 2019. PMID: 31336805 Free PMC article.
Targeted sequencing reveals expanded genetic diversity of human transfer RNAs.
Berg MD, Giguere DJ, Dron JS, Lant JT, Genereaux J, Liao C, Wang J, Robinson JF, Gloor GB, Hegele RA, O'Donoghue P, Brandl CJ. Berg MD, et al. RNA Biol. 2019 Nov;16(11):1574-1585. doi: 10.1080/15476286.2019.1646079. Epub 2019 Aug 13. RNA Biol. 2019. PMID: 31407949 Free PMC article.
193 results