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102 results

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Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient-induced pluripotent stem cell-derived retinal pigment epithelium cells.
Georgiou M, Yang C, Atkinson R, Pan KT, Buskin A, Molina MM, Collin J, Al-Aama J, Goertler F, Ludwig SEJ, Davey T, Lührmann R, Nagaraja-Grellscheid S, Johnson CA, Ali R, Armstrong L, Korolchuk V, Urlaub H, Mozaffari-Jovin S, Lako M. Georgiou M, et al. Among authors: korolchuk v. Clin Transl Med. 2022 Mar;12(3):e759. doi: 10.1002/ctm2.759. Clin Transl Med. 2022. PMID: 35297555 Free PMC article.
An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure.
Hallam D, Collin J, Bojic S, Chichagova V, Buskin A, Xu Y, Lafage L, Otten EG, Anyfantis G, Mellough C, Przyborski S, Alharthi S, Korolchuk V, Lotery A, Saretzki G, McKibbin M, Armstrong L, Steel D, Kavanagh D, Lako M. Hallam D, et al. Among authors: korolchuk v. Stem Cells. 2017 Nov;35(11):2305-2320. doi: 10.1002/stem.2708. Epub 2017 Oct 9. Stem Cells. 2017. PMID: 28913923 Free PMC article.
Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function.
Cerniauskas E, Kurzawa-Akanbi M, Xie L, Hallam D, Moya-Molina M, White K, Steel D, Doherty M, Whitfield P, Al-Aama J, Armstrong L, Kavanagh D, Lambris JD, Korolchuk VI, Harris C, Lako M. Cerniauskas E, et al. Stem Cells Transl Med. 2020 Dec;9(12):1585-1603. doi: 10.1002/sctm.20-0211. Epub 2020 Aug 20. Stem Cells Transl Med. 2020. PMID: 32815311 Free PMC article.
Autophagy: 'Self-Eating' Your Way to Longevity.
Pattison CJ, Korolchuk VI. Pattison CJ, et al. Subcell Biochem. 2018;90:25-47. doi: 10.1007/978-981-13-2835-0_2. Subcell Biochem. 2018. PMID: 30779005 Review.
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models.
Kataura T, Sedlackova L, Sun C, Kocak G, Wilson N, Banks P, Hayat F, Trushin S, Trushina E, Maddocks ODK, Oblong JE, Miwa S, Imoto M, Saiki S, Erskine D, Migaud ME, Sarkar S, Korolchuk VI. Kataura T, et al. Among authors: korolchuk vi. Cell Death Dis. 2024 May 31;15(5):382. doi: 10.1038/s41419-024-06770-y. Cell Death Dis. 2024. PMID: 38821960 Free PMC article.
Nutrient sensing, growth and senescence.
Carroll B, Korolchuk VI. Carroll B, et al. FEBS J. 2018 Jun;285(11):1948-1958. doi: 10.1111/febs.14400. Epub 2018 Feb 15. FEBS J. 2018. PMID: 29405586 Free PMC article. Review.
The pROS of Autophagy in Neuronal Health.
Sedlackova L, Kelly G, Korolchuk VI. Sedlackova L, et al. J Mol Biol. 2020 Apr 3;432(8):2546-2559. doi: 10.1016/j.jmb.2020.01.020. Epub 2020 Jan 30. J Mol Biol. 2020. PMID: 32006535 Free PMC article. Review.
Autophagy in Neurodegenerative Diseases.
Korolchuk VI, Sarkar S, Fanto M. Korolchuk VI, et al. J Mol Biol. 2020 Apr 3;432(8):2445-2448. doi: 10.1016/j.jmb.2020.03.005. Epub 2020 Mar 10. J Mol Biol. 2020. PMID: 32169483 No abstract available.
102 results