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T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.
Suan D, Nguyen A, Moran I, Bourne K, Hermes JR, Arshi M, Hampton HR, Tomura M, Miwa Y, Kelleher AD, Kaplan W, Deenick EK, Tangye SG, Brink R, Chtanova T, Phan TG. Suan D, et al. Among authors: phan tg. Immunity. 2015 Apr 21;42(4):704-18. doi: 10.1016/j.immuni.2015.03.002. Epub 2015 Mar 31. Immunity. 2015. PMID: 25840682 Free article.
Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency.
Deenick EK, Morey A, Danta M, Emmett L, Fay K, Gracie G, Ma CS, Macintosh R, Smith SABC, Sasson SC, Sewell WA, Cowley M, Tangye SG, Kelleher AD; CIRCA; Phan TG. Deenick EK, et al. Among authors: phan tg. J Clin Immunol. 2018 Feb;38(2):159-162. doi: 10.1007/s10875-018-0477-z. Epub 2018 Jan 19. J Clin Immunol. 2018. PMID: 29350338 No abstract available.
Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes.
Moran I, Nguyen A, Khoo WH, Butt D, Bourne K, Young C, Hermes JR, Biro M, Gracie G, Ma CS, Munier CML, Luciani F, Zaunders J, Parker A, Kelleher AD, Tangye SG, Croucher PI, Brink R, Read MN, Phan TG. Moran I, et al. Among authors: phan tg. Nat Commun. 2018 Aug 22;9(1):3372. doi: 10.1038/s41467-018-05772-7. Nat Commun. 2018. PMID: 30135429 Free PMC article.
Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency.
Yap JY, Moens L, Lin MW, Kane A, Kelleher A, Toong C, Wu KHC, Sewell WA, Phan TG, Hollway GE, Enthoven K, Gray PE, Casas-Martin J, Wouters C, De Somer L, Hershfield M, Bucciol G, Delafontaine S, Ma CS, Tangye SG, Meyts I. Yap JY, et al. Among authors: phan tg. J Clin Immunol. 2021 Nov;41(8):1915-1935. doi: 10.1007/s10875-021-01141-0. Epub 2021 Oct 17. J Clin Immunol. 2021. PMID: 34657246 Free PMC article.
Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19.
Khoo WH, Jackson K, Phetsouphanh C, Zaunders JJ, Alquicira-Hernandez J, Yazar S, Ruiz-Diaz S, Singh M, Dhenni R, Kyaw W, Tea F, Merheb V, Lee FXZ, Burrell R, Howard-Jones A, Koirala A, Zhou L, Yuksel A, Catchpoole DR, Lai CL, Vitagliano TL, Rouet R, Christ D, Tang B, West NP, George S, Gerrard J, Croucher PI, Kelleher AD, Goodnow CG, Sprent JD, Powell JE, Brilot F, Nanan R, Hsu PS, Deenick EK, Britton PN, Phan TG. Khoo WH, et al. Among authors: phan tg. Clin Immunol. 2023 Jan;246:109209. doi: 10.1016/j.clim.2022.109209. Epub 2022 Dec 17. Clin Immunol. 2023. PMID: 36539107 Free PMC article.
High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells.
Phetsouphanh C, Khoo WH, Jackson K, Klemm V, Howe A, Aggarwal A, Akerman A, Milogiannakis V, Stella AO, Rouet R, Schofield P, Faulks ML, Law H, Danwilai T, Starr M, Munier CML, Christ D, Singh M, Croucher PI, Brilot-Turville F, Turville S, Phan TG, Dore GJ, Darley D, Cunningham P, Matthews GV, Kelleher AD, Zaunders JJ. Phetsouphanh C, et al. Among authors: phan tg. Front Immunol. 2022 Dec 5;13:1032911. doi: 10.3389/fimmu.2022.1032911. eCollection 2022. Front Immunol. 2022. PMID: 36544780 Free PMC article.
β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Thai LM, O'Reilly L, Reibe-Pal S, Sue N, Holliday H, Small L, Schmitz-Peiffer C, Dhenni R, Wang-Wei Tsai V, Norris N, Yau B, Zhang X, Lee K, Yan C, Shi YC, Kebede MA, Brink R, Cooney GJ, Irvine KM, Breit SN, Phan TG, Swarbrick A, Biden TJ. Thai LM, et al. Among authors: phan tg. iScience. 2023 Mar 22;26(4):106477. doi: 10.1016/j.isci.2023.106477. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091234 Free PMC article.
SnapShot: Interactions between B Cells and T Cells.
Tangye SG, Brink R, Goodnow CC, Phan TG. Tangye SG, et al. Among authors: phan tg. Cell. 2015 Aug 13;162(4):926-6.e1. doi: 10.1016/j.cell.2015.07.055. Cell. 2015. PMID: 26276638 Free article.
400 results