Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency

J Clin Immunol. 2018 Feb;38(2):159-162. doi: 10.1007/s10875-018-0477-z. Epub 2018 Jan 19.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Common Variable Immunodeficiency / complications*
  • Common Variable Immunodeficiency / diagnosis
  • Common Variable Immunodeficiency / drug therapy
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Immunophenotyping
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use*
  • Lymphocytes / drug effects*
  • Lymphocytes / immunology*
  • Lymphocytes / metabolism
  • Middle Aged
  • Positron Emission Tomography Computed Tomography
  • Sirolimus / pharmacology
  • Sirolimus / therapeutic use*
  • Symptom Assessment
  • Thrombocytopenia / diagnosis
  • Thrombocytopenia / drug therapy*
  • Thrombocytopenia / etiology*
  • Treatment Outcome

Substances

  • Immunoglobulins, Intravenous
  • Immunosuppressive Agents
  • Sirolimus