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Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using 11C-BU99008 PET and its relationship with amyloid load.
Calsolaro V, Matthews PM, Donat CK, Livingston NR, Femminella GD, Guedes SS, Myers J, Fan Z, Tyacke RJ, Venkataraman AV, Perneczky R, Gunn R, Rabiner EA, Gentleman S, Parker CA, Murphy PS, Wren PB, Hinz R, Sastre M, Nutt DJ, Edison P. Calsolaro V, et al. Among authors: parker ca. Mol Psychiatry. 2021 Oct;26(10):5848-5855. doi: 10.1038/s41380-021-01193-z. Epub 2021 Jul 15. Mol Psychiatry. 2021. PMID: 34267329 Free PMC article.
Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.
Pike VW, Taliani S, Lohith TG, Owen DR, Pugliesi I, Da Pozzo E, Hong J, Zoghbi SS, Gunn RN, Parker CA, Rabiner EA, Fujita M, Innis RB, Martini C, Da Settimo F. Pike VW, et al. Among authors: parker ca. J Med Chem. 2011 Jan 13;54(1):366-73. doi: 10.1021/jm101230g. Epub 2010 Dec 6. J Med Chem. 2011. PMID: 21133364 Free PMC article.
Mixed-affinity binding in humans with 18-kDa translocator protein ligands.
Owen DR, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, Innis RB, Pike VW, Reynolds R, Matthews PM, Parker CA. Owen DR, et al. Among authors: parker ca. J Nucl Med. 2011 Jan;52(1):24-32. doi: 10.2967/jnumed.110.079459. Epub 2010 Dec 13. J Nucl Med. 2011. PMID: 21149489 Free PMC article.
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
Owen DR, Yeo AJ, Gunn RN, Song K, Wadsworth G, Lewis A, Rhodes C, Pulford DJ, Bennacef I, Parker CA, StJean PL, Cardon LR, Mooser VE, Matthews PM, Rabiner EA, Rubio JP. Owen DR, et al. Among authors: parker ca. J Cereb Blood Flow Metab. 2012 Jan;32(1):1-5. doi: 10.1038/jcbfm.2011.147. Epub 2011 Oct 19. J Cereb Blood Flow Metab. 2012. PMID: 22008728 Free PMC article.
124 results