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Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines-Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials.
Buchman TG, Draghia-Akli R, Adam SJ, Aggarwal NR, Fessel JP, Higgs ES, Menetski JP, Read SW, Hughes EA; Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines (ACTIV) Therapeutics Clinical Working Group. Buchman TG, et al. Among authors: hughes ea. Crit Care Med. 2021 Nov 1;49(11):1963-1973. doi: 10.1097/CCM.0000000000005295. Crit Care Med. 2021. PMID: 34495876 Free PMC article. Review.
The NIH-led research response to COVID-19.
Collins F, Adam S, Colvis C, Desrosiers E, Draghia-Akli R, Fauci A, Freire M, Gibbons G, Hall M, Hughes E, Jansen K, Kurilla M, Lane HC, Lowy D, Marks P, Menetski J, Pao W, Pérez-Stable E, Purcell L, Read S, Rutter J, Santos M, Schwetz T, Shuren J, Stenzel T, Stoffels P, Tabak L, Tountas K, Tromberg B, Wholley D, Woodcock J, Young J. Collins F, et al. Science. 2023 Feb 3;379(6631):441-444. doi: 10.1126/science.adf5167. Epub 2023 Feb 2. Science. 2023. PMID: 36730407
An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism.
Lees JA, Dias JM, Rajamohan F, Fortin JP, O'Connor R, Kong JX, Hughes EAG, Fisher EL, Tuttle JB, Lovett G, Kormos BL, Unwalla RJ, Zhang L, Dechert Schmitt AM, Zhou D, Moran M, Stevens KA, Fennell KF, Varghese AE, Maxwell A, Cote EE, Zhang Y, Han S. Lees JA, et al. Among authors: hughes eag. Nat Commun. 2023 Sep 23;14(1):5938. doi: 10.1038/s41467-023-41646-3. Nat Commun. 2023. PMID: 37741852 Free PMC article.
154 results