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TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma.
Fujimoto K, Arita H, Satomi K, Yamasaki K, Matsushita Y, Nakamura T, Miyakita Y, Umehara T, Kobayashi K, Tamura K, Tanaka S, Higuchi F, Okita Y, Kanemura Y, Fukai J, Sakamoto D, Uda T, Machida R, Kuchiba A, Maehara T, Nagane M, Nishikawa R, Suzuki H, Shibuya M, Komori T, Narita Y, Ichimura K. Fujimoto K, et al. Among authors: maehara t. Acta Neuropathol. 2021 Aug;142(2):323-338. doi: 10.1007/s00401-021-02337-9. Epub 2021 Jun 20. Acta Neuropathol. 2021. PMID: 34148105
Low incidence of seizures in patients with chronic subdural haematoma.
Ohno K, Maehara T, Ichimura K, Suzuki R, Hirakawa K, Monma S. Ohno K, et al. Among authors: maehara t. J Neurol Neurosurg Psychiatry. 1993 Nov;56(11):1231-3. doi: 10.1136/jnnp.56.11.1231. J Neurol Neurosurg Psychiatry. 1993. PMID: 8229039 Free PMC article. Review.
Human chorionic gonadotropin is expressed virtually in all intracranial germ cell tumors.
Takami H, Fukushima S, Fukuoka K, Suzuki T, Yanagisawa T, Matsushita Y, Nakamura T, Arita H, Mukasa A, Saito N, Kanamori M, Kumabe T, Tominaga T, Kobayashi K, Nagane M, Iuchi T, Tamura K, Maehara T, Sugiyama K, Nakada M, Kanemura Y, Nonaka M, Yokogami K, Takeshima H, Narita Y, Shibui S, Nakazato Y, Nishikawa R, Ichimura K, Matsutani M. Takami H, et al. Among authors: maehara t. J Neurooncol. 2015 Aug;124(1):23-32. doi: 10.1007/s11060-015-1809-y. Epub 2015 May 21. J Neurooncol. 2015. PMID: 25994796
Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomas.
Nakamura T, Tateishi K, Niwa T, Matsushita Y, Tamura K, Kinoshita M, Tanaka K, Fukushima S, Takami H, Arita H, Kubo A, Shuto T, Ohno M, Miyakita Y, Kocialkowski S, Sasayama T, Hashimoto N, Maehara T, Shibui S, Ushijima T, Kawahara N, Narita Y, Ichimura K. Nakamura T, et al. Among authors: maehara t. Neuropathol Appl Neurobiol. 2016 Apr;42(3):279-90. doi: 10.1111/nan.12259. Epub 2015 Jul 20. Neuropathol Appl Neurobiol. 2016. PMID: 26111727
Recurrent neomorphic mutations of MTOR in central nervous system and testicular germ cell tumors may be targeted for therapy.
Ichimura K, Fukushima S, Totoki Y, Matsushita Y, Otsuka A, Tomiyama A, Niwa T, Takami H, Nakamura T, Suzuki T, Fukuoka K, Yanagisawa T, Mishima K, Nakazato Y, Hosoda F, Narita Y, Shibui S, Yoshida A, Mukasa A, Saito N, Kumabe T, Kanamori M, Tominaga T, Kobayashi K, Shimizu S, Nagane M, Iuchi T, Mizoguchi M, Yoshimoto K, Tamura K, Maehara T, Sugiyama K, Nakada M, Sakai K, Kanemura Y, Nonaka M, Asai A, Yokogami K, Takeshima H, Kawahara N, Takayama T, Yao M, Kato M, Nakamura H, Hama N, Sakai R, Ushijima T, Matsutani M, Shibata T, Nishikawa R; Intracranial Germ Cell Tumor Genome Analysis Consortium. Ichimura K, et al. Among authors: maehara t. Acta Neuropathol. 2016 Jun;131(6):889-901. doi: 10.1007/s00401-016-1557-x. Epub 2016 Mar 8. Acta Neuropathol. 2016. PMID: 26956871
A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.
Arita H, Yamasaki K, Matsushita Y, Nakamura T, Shimokawa A, Takami H, Tanaka S, Mukasa A, Shirahata M, Shimizu S, Suzuki K, Saito K, Kobayashi K, Higuchi F, Uzuka T, Otani R, Tamura K, Sumita K, Ohno M, Miyakita Y, Kagawa N, Hashimoto N, Hatae R, Yoshimoto K, Shinojima N, Nakamura H, Kanemura Y, Okita Y, Kinoshita M, Ishibashi K, Shofuda T, Kodama Y, Mori K, Tomogane Y, Fukai J, Fujita K, Terakawa Y, Tsuyuguchi N, Moriuchi S, Nonaka M, Suzuki H, Shibuya M, Maehara T, Saito N, Nagane M, Kawahara N, Ueki K, Yoshimine T, Miyaoka E, Nishikawa R, Komori T, Narita Y, Ichimura K. Arita H, et al. Among authors: maehara t. Acta Neuropathol Commun. 2016 Aug 8;4(1):79. doi: 10.1186/s40478-016-0351-2. Acta Neuropathol Commun. 2016. PMID: 27503138 Free PMC article.
Genome-wide DNA methylation profiling identifies primary central nervous system lymphoma as a distinct entity different from systemic diffuse large B-cell lymphoma.
Nakamura T, Yamashita S, Fukumura K, Nakabayashi J, Tanaka K, Tamura K, Tateishi K, Kinoshita M, Fukushima S, Takami H, Fukuoka K, Yamazaki K, Matsushita Y, Ohno M, Miyakita Y, Shibui S, Kubo A, Shuto T, Kocialkowski S, Yamanaka S, Mukasa A, Sasayama T, Mishima K, Maehara T, Kawahara N, Nagane M, Narita Y, Mano H, Ushijima T, Ichimura K. Nakamura T, et al. Among authors: maehara t. Acta Neuropathol. 2017 Feb;133(2):321-324. doi: 10.1007/s00401-016-1664-8. Epub 2017 Jan 5. Acta Neuropathol. 2017. PMID: 28058506 No abstract available.
LAPTM4B-35 is a novel prognostic factor for glioblastoma.
Dong X, Tamura K, Kobayashi D, Ando N, Sumita K, Maehara T. Dong X, et al. Among authors: maehara t. J Neurooncol. 2017 Apr;132(2):295-303. doi: 10.1007/s11060-017-2369-0. Epub 2017 Jan 18. J Neurooncol. 2017. PMID: 28097442
674 results