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A single amino acid Gly-tag enables metal-free protein purification.
Chem Sci. 2020 Oct 26;11(48):13137-13142. doi: 10.1039/d0sc01153c.
Chem Sci. 2020.
PMID: 34094495
Free PMC article.
Linchpins empower promiscuous electrophiles to enable site-selective modification of histidine and aspartic acid in proteins.
Rawale DG, Thakur K, Sreekumar P, T K S, A R, Adusumalli SR, Mishra RK, Rai V.
Rawale DG, et al.
Chem Sci. 2021 Apr 9;12(19):6732-6736. doi: 10.1039/d1sc00335f.
Chem Sci. 2021.
PMID: 34040749
Free PMC article.
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Aldehydes can switch the chemoselectivity of electrophiles in protein labeling.
Adusumalli SR, Rawale DG, Rai V.
Adusumalli SR, et al. Among authors: rawale dg.
Org Biomol Chem. 2018 Dec 12;16(48):9377-9381. doi: 10.1039/c8ob02897d.
Org Biomol Chem. 2018.
PMID: 30516786
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Single-site glycine-specific labeling of proteins.
Purushottam L, Adusumalli SR, Singh U, Unnikrishnan VB, Rawale DG, Gujrati M, Mishra RK, Rai V.
Purushottam L, et al. Among authors: rawale dg.
Nat Commun. 2019 Jun 10;10(1):2539. doi: 10.1038/s41467-019-10503-7.
Nat Commun. 2019.
PMID: 31182711
Free PMC article.
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Chemoselective and Site-Selective Lysine-Directed Lysine Modification Enables Single-Site Labeling of Native Proteins.
Adusumalli SR, Rawale DG, Thakur K, Purushottam L, Reddy NC, Kalra N, Shukla S, Rai V.
Adusumalli SR, et al. Among authors: rawale dg.
Angew Chem Int Ed Engl. 2020 Jun 22;59(26):10332-10336. doi: 10.1002/anie.202000062. Epub 2020 Apr 20.
Angew Chem Int Ed Engl. 2020.
PMID: 32171045
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Single-Site Labeling of Native Proteins Enabled by a Chemoselective and Site-Selective Chemical Technology.
Adusumalli SR, Rawale DG, Singh U, Tripathi P, Paul R, Kalra N, Mishra RK, Shukla S, Rai V.
Adusumalli SR, et al. Among authors: rawale dg.
J Am Chem Soc. 2018 Nov 7;140(44):15114-15123. doi: 10.1021/jacs.8b10490. Epub 2018 Oct 26.
J Am Chem Soc. 2018.
PMID: 30336012
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Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.
Reddi RN, Rogel A, Gabizon R, Rawale DG, Harish B, Marom S, Tivon B, Arbel YS, Gurwicz N, Oren R, David K, Liu J, Duberstein S, Itkin M, Malitsky S, Barr H, Katz BZ, Herishanu Y, Shachar I, Shulman Z, London N.
Reddi RN, et al. Among authors: rawale dg.
J Am Chem Soc. 2023 Feb 15;145(6):3346-3360. doi: 10.1021/jacs.2c08853. Epub 2023 Feb 4.
J Am Chem Soc. 2023.
PMID: 36738297
Free PMC article.
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Human Behavior-Inspired Linchpin-Directed Catalysis for Traceless Precision Labeling of Lysine in Native Proteins.
Thakur K, T K S, Singh SK, V R, Rawale DG, Adusumalli SR, Kalra N, Shukla S, Mishra RK, Rai V.
Thakur K, et al. Among authors: rawale dg.
Bioconjug Chem. 2022 Dec 21;33(12):2370-2380. doi: 10.1021/acs.bioconjchem.2c00454. Epub 2022 Nov 16.
Bioconjug Chem. 2022.
PMID: 36383773
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