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Merging C(sp3)-H activation with DNA-encoding.
Fan Z, Zhao S, Liu T, Shen PX, Cui ZN, Zhuang Z, Shao Q, Chen JS, Ratnayake AS, Flanagan ME, Kölmel DK, Piotrowski DW, Richardson P, Yu JQ. Fan Z, et al. Among authors: flanagan me. Chem Sci. 2020 Sep 7;11(45):12282-12288. doi: 10.1039/d0sc03935g. Chem Sci. 2020. PMID: 34094436 Free PMC article.
RASS-Enabled S/P-C and S-N Bond Formation for DEL Synthesis.
Flood DT, Zhang X, Fu X, Zhao Z, Asai S, Sanchez BB, Sturgell EJ, Vantourout JC, Richardson P, Flanagan ME, Piotrowski DW, Kölmel DK, Wan J, Tsai MH, Chen JS, Baran PS, Dawson PE. Flood DT, et al. Among authors: flanagan me. Angew Chem Int Ed Engl. 2020 May 4;59(19):7377-7383. doi: 10.1002/anie.201915493. Epub 2020 Mar 11. Angew Chem Int Ed Engl. 2020. PMID: 32050046 Free PMC article.
Photoredox cross-electrophile coupling in DNA-encoded chemistry.
Kölmel DK, Ratnayake AS, Flanagan ME. Kölmel DK, et al. Among authors: flanagan me. Biochem Biophys Res Commun. 2020 Dec 3;533(2):201-208. doi: 10.1016/j.bbrc.2020.04.028. Epub 2020 May 12. Biochem Biophys Res Commun. 2020. PMID: 32414574
Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support.
Flood DT, Asai S, Zhang X, Wang J, Yoon L, Adams ZC, Dillingham BC, Sanchez BB, Vantourout JC, Flanagan ME, Piotrowski DW, Richardson P, Green SA, Shenvi RA, Chen JS, Baran PS, Dawson PE. Flood DT, et al. Among authors: flanagan me. J Am Chem Soc. 2019 Jun 26;141(25):9998-10006. doi: 10.1021/jacs.9b03774. Epub 2019 Jun 12. J Am Chem Soc. 2019. PMID: 31136164 Free PMC article.
Photocatalytic [2 + 2] Cycloaddition in DNA-Encoded Chemistry.
Kölmel DK, Ratnayake AS, Flanagan ME, Tsai MH, Duan C, Song C. Kölmel DK, et al. Among authors: flanagan me. Org Lett. 2020 Apr 17;22(8):2908-2913. doi: 10.1021/acs.orglett.0c00574. Epub 2020 Apr 2. Org Lett. 2020. PMID: 32239950
Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS).
Ratnayake AS, Flanagan ME, Foley TL, Hultgren SL, Bellenger J, Montgomery JI, Lall MS, Liu B, Ryder T, Kölmel DK, Shavnya A, Feng X, Lefker B, Byrnes LJ, Sahasrabudhe PV, Farley KA, Chen S, Wan J. Ratnayake AS, et al. Among authors: flanagan me. Bioorg Med Chem. 2021 Jul 1;41:116205. doi: 10.1016/j.bmc.2021.116205. Epub 2021 May 11. Bioorg Med Chem. 2021. PMID: 34000509
162 results