Wang H - Search Results

1

Discovery of imidazopyrrolopyridines derivatives as novel and selective inhibitors of JAK2.

Xu P, Shen P, Wang H, Qin L, Ren J, Sun Q, Ge R, Bian J, Zhong Y, Li Z, Wang J, Qiu Z. Xu P, et al. Among authors: wang h, wang j. Eur J Med Chem. 2021 Jun 5;218:113394. doi: 10.1016/j.ejmech.2021.113394. Epub 2021 Mar 26. Eur J Med Chem. 2021. PMID: 33813153

2

Novel 5-carboxy-8-HQ based histone demethylase JMJD2A inhibitors: introduction of an additional carboxyl group at the C-2 position of quinoline.

Feng T, Li D, Wang H, Zhuang J, Liu F, Bao Q, Lei Y, Chen W, Zhang X, Xu X, Sun H, You Q, Guo X. Feng T, et al. Among authors: wang h. Eur J Med Chem. 2015 Nov 13;105:145-55. doi: 10.1016/j.ejmech.2015.09.013. Epub 2015 Sep 10. Eur J Med Chem. 2015. PMID: 26491978

3

Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors.

Xu G, Zhang Y, Wang H, Guo Z, Wang X, Li X, Chang S, Sun T, Yu Z, Xu T, Zhao L, Wang Y, Yu W. Xu G, et al. Among authors: wang h, wang x, wang y. Eur J Med Chem. 2020 Jul 15;198:112354. doi: 10.1016/j.ejmech.2020.112354. Epub 2020 Apr 29. Eur J Med Chem. 2020. PMID: 32387837

4

Synthesis and biological evaluation of 4-(pyridine-4-oxy)-3-(tetrahydro-2H-pyran-4-yl)-pyrazole derivatives as novel, potent of ALK5 receptor inhibitors.

Wang Z, Zhang Y, Wang H, Wang X, Yu Z, Zhao L. Wang Z, et al. Among authors: wang h, wang x. Bioorg Med Chem Lett. 2022 Apr 1;61:128552. doi: 10.1016/j.bmcl.2022.128552. Epub 2022 Jan 18. Bioorg Med Chem Lett. 2022. PMID: 35051574

5

Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2).

Feng T, Wang H, Su H, Lu H, Yu L, Zhang X, Sun H, You Q. Feng T, et al. Among authors: wang h. Bioorg Med Chem. 2013 Sep 1;21(17):5339-54. doi: 10.1016/j.bmc.2013.06.009. Epub 2013 Jun 15. Bioorg Med Chem. 2013. PMID: 23820574

6

The discovery of novel histone lysine methyltransferase G9a inhibitors (part 1): molecular design based on a series of substituted 2,4-diamino-7- aminoalkoxyquinazoline by molecular-docking-guided 3D quantitative structure-activity relationship studies.

Feng T, Wang H, Zhang X, Sun H, You Q. Feng T, et al. Among authors: wang h. Med Chem. 2014 Jun;10(4):426-40. doi: 10.2174/15734064113096660068. Med Chem. 2014. PMID: 24151879

7

Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.

Plewe MB, Butler SL, Dress KR, Hu Q, Johnson TW, Kuehler JE, Kuki A, Lam H, Liu W, Nowlin D, Peng Q, Rahavendran SV, Tanis SP, Tran KT, Wang H, Yang A, Zhang J. Plewe MB, et al. Among authors: wang h. J Med Chem. 2009 Nov 26;52(22):7211-9. doi: 10.1021/jm900862n. J Med Chem. 2009. PMID: 19873974

8

Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors.

Johnson TW, Tanis SP, Butler SL, Dalvie D, Delisle DM, Dress KR, Flahive EJ, Hu Q, Kuehler JE, Kuki A, Liu W, McClellan GA, Peng Q, Plewe MB, Richardson PF, Smith GL, Solowiej J, Tran KT, Wang H, Yu X, Zhang J, Zhu H. Johnson TW, et al. Among authors: wang h. J Med Chem. 2011 May 12;54(9):3393-417. doi: 10.1021/jm200208d. Epub 2011 Apr 13. J Med Chem. 2011. PMID: 21446745

9

Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kα and mTOR.

Le PT, Cheng H, Ninkovic S, Plewe M, Huang X, Wang H, Bagrodia S, Sun S, Knighton DR, LaFleur Rogers CM, Pannifer A, Greasley S, Dalvie D, Zhang E. Le PT, et al. Among authors: wang h. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5098-103. doi: 10.1016/j.bmcl.2012.05.100. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22749419

10

Synthesis and Biological Evaluation of Spirocyclic Chromane Derivatives as a Potential Treatment of Prostate Cancer.

Feng L, Yu S, Wang H, Yang S, Li X, Dai H, Zhao L, Jiang C, Wang Y. Feng L, et al. Among authors: wang h, wang y. Molecules. 2021 May 25;26(11):3162. doi: 10.3390/molecules26113162. Molecules. 2021. PMID: 34070610 Free PMC article.

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