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CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R. Deleye Y, et al. Among authors: paumelle r. J Biol Chem. 2020 Dec 11;295(50):17310-17322. doi: 10.1074/jbc.RA120.012543. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037071 Free PMC article.
PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K. Bougarne N, et al. Among authors: paumelle r. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7397-402. doi: 10.1073/pnas.0806742106. Epub 2009 Apr 17. Proc Natl Acad Sci U S A. 2009. PMID: 19376972 Free PMC article.
LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice.
Touvier T, Conte-Auriol F, Briand O, Cudejko C, Paumelle R, Caron S, Baugé E, Rouillé Y, Salles JP, Staels B, Bailleul B. Touvier T, et al. Among authors: paumelle r. J Clin Invest. 2009 Dec;119(12):3830-8. doi: 10.1172/JCI34997. Epub 2009 Nov 9. J Clin Invest. 2009. PMID: 19907080 Free PMC article.
37 results