Peroxisome proliferator-activated receptors mediate pleiotropic actions of statins

Circ Res. 2007 May 25;100(10):1394-5. doi: 10.1161/01.RES.0000269334.42814.d2.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cholesterol, LDL / metabolism
  • Cyclooxygenase 2 / genetics*
  • Extracellular Signal-Regulated MAP Kinases / physiology
  • Gene Expression Regulation, Enzymologic / drug effects*
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology*
  • Macrophages / drug effects
  • Macrophages / metabolism
  • Mice
  • PPAR alpha / drug effects*
  • PPAR alpha / physiology
  • PPAR gamma / drug effects*
  • PPAR gamma / physiology
  • p38 Mitogen-Activated Protein Kinases / physiology

Substances

  • Cholesterol, LDL
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • PPAR alpha
  • PPAR gamma
  • Cyclooxygenase 2
  • Extracellular Signal-Regulated MAP Kinases
  • p38 Mitogen-Activated Protein Kinases