Miele M - Search Results

1

Chemoselective Homologation-Deoxygenation Strategy Enabling the Direct Conversion of Carbonyls into (n+1)-Halomethyl-Alkanes.

Miele M, Citarella A, Langer T, Urban E, Zehl M, Holzer W, Ielo L, Pace V. Miele M, et al. Org Lett. 2020 Oct 2;22(19):7629-7634. doi: 10.1021/acs.orglett.0c02831. Epub 2020 Sep 10. Org Lett. 2020. PMID: 32910659 Free PMC article.

2

Chemoselective reduction of isothiocyanates to thioformamides mediated by the Schwartz reagent.

de la Vega-Hernández K, Senatore R, Miele M, Urban E, Holzer W, Pace V. de la Vega-Hernández K, et al. Among authors: miele m. Org Biomol Chem. 2019 Feb 13;17(7):1970-1978. doi: 10.1039/c8ob02312c. Org Biomol Chem. 2019. PMID: 30362485

3

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF₂-Carbene Equivalent.

Miele M, Citarella A, Micale N, Holzer W, Pace V. Miele M, et al. Org Lett. 2019 Oct 18;21(20):8261-8265. doi: 10.1021/acs.orglett.9b03024. Epub 2019 Oct 10. Org Lett. 2019. PMID: 31599599

4

Highly chemoselective difluoromethylative homologation of iso(thio)cyanates: expeditious access to unprecedented α,α-difluoro(thio)amides.

Miele M, D'Orsi R, Sridharan V, Holzer W, Pace V. Miele M, et al. Chem Commun (Camb). 2019 Oct 24;55(86):12960-12963. doi: 10.1039/c9cc06929a. Chem Commun (Camb). 2019. PMID: 31602439

5

Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-opening en route to halohydrins.

Ielo L, Miele M, Pillari V, Senatore R, Mirabile S, Gitto R, Holzer W, Alcántara AR, Pace V. Ielo L, et al. Among authors: miele m. Org Biomol Chem. 2021 Mar 11;19(9):2038-2043. doi: 10.1039/d0ob02407d. Org Biomol Chem. 2021. PMID: 33599644

6

Direct and straightforward transfer of C1 functionalized synthons to phosphorous electrophiles for accessing gem-P-containing methanes.

Touqeer S, Ielo L, Miele M, Urban E, Holzer W, Pace V. Touqeer S, et al. Among authors: miele m. Org Biomol Chem. 2021 Mar 21;19(11):2425-2429. doi: 10.1039/d1ob00273b. Epub 2021 Mar 5. Org Biomol Chem. 2021. PMID: 33666635

7

Straightforward synthesis of bench-stable heteroatom-centered difluoromethylated entities via controlled nucleophilic transfer from activated TMSCHF₂.

Miele M, Castoldi L, Simeone X, Holzer W, Pace V. Miele M, et al. Chem Commun (Camb). 2022 May 10;58(38):5761-5764. doi: 10.1039/d2cc00886f. Chem Commun (Camb). 2022. PMID: 35450981 Free article.

8

Application of Biobased Solvents in Asymmetric Catalysis.

Miele M, Pillari V, Pace V, Alcántara AR, de Gonzalo G. Miele M, et al. Molecules. 2022 Oct 8;27(19):6701. doi: 10.3390/molecules27196701. Molecules. 2022. PMID: 36235236 Free PMC article. Review.

9

Novel alpha6 preferring GABA-A receptor ligands based on loreclezole.

Simeone X, Ernst M, Seidel T, Heider J, Enz D, Monticelli S, Vogel FD, Koniuszewski F, Langer T, Scholze P, Pace V, Miele M. Simeone X, et al. Among authors: miele m. Eur J Med Chem. 2022 Dec 15;244:114780. doi: 10.1016/j.ejmech.2022.114780. Epub 2022 Sep 17. Eur J Med Chem. 2022. PMID: 36279694

10

eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.

Boyer JA, Sharma M, Dorso MA, Mai N, Amor C, Reiter JM, Kannan R, Gadal S, Xu J, Miele M, Li Z, Chen X, Chang Q, Pareja F, Worland S, Warner D, Sperry S, Chiang GG, Thompson PA, Yang G, Ouerfelli O, de Stanchina E, Wendel HG, Rosen EY, Chandarlapaty S, Rosen N. Boyer JA, et al. Among authors: miele m. bioRxiv [Preprint]. 2024 May 11:2024.05.08.593195. doi: 10.1101/2024.05.08.593195. bioRxiv. 2024. PMID: 38766126 Free PMC article. Preprint.

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