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A pan-cancer analysis reveals nonstop extension mutations causing SMAD4 tumour suppressor degradation.
Nat Cell Biol. 2020 Aug;22(8):999-1010. doi: 10.1038/s41556-020-0551-7. Epub 2020 Jul 27.
Nat Cell Biol. 2020.
PMID: 32719554
Chimeric oligonucleotides combining guide RNA and single-stranded DNA repair template effectively induce precision gene editing.
Ghosh A, Myacheva K, Riester M, Schmidt C, Diederichs S.
Ghosh A, et al. Among authors: myacheva k.
RNA Biol. 2022;19(1):588-593. doi: 10.1080/15476286.2022.2067713. Epub 2021 Dec 31.
RNA Biol. 2022.
PMID: 35465826
Free PMC article.
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Challenges of CRISPR/Cas9 applications for long non-coding RNA genes.
Goyal A, Myacheva K, Groß M, Klingenberg M, Duran Arqué B, Diederichs S.
Goyal A, et al. Among authors: myacheva k.
Nucleic Acids Res. 2017 Feb 17;45(3):e12. doi: 10.1093/nar/gkw883.
Nucleic Acids Res. 2017.
PMID: 28180319
Free PMC article.
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LINC00261 and the Adjacent Gene FOXA2 Are Epithelial Markers and Are Suppressed during Lung Cancer Tumorigenesis and Progression.
Dhamija S, Becker AC, Sharma Y, Myacheva K, Seiler J, Diederichs S.
Dhamija S, et al. Among authors: myacheva k.
Noncoding RNA. 2018 Dec 28;5(1):2. doi: 10.3390/ncrna5010002.
Noncoding RNA. 2018.
PMID: 30597925
Free PMC article.
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CRISPRi screening identifies CASP8AP2 as an essential viability factor in lung cancer controlling tumor cell death via the AP-1 pathway.
Myacheva K, Walsh A, Riester M, Pelos G, Carl J, Diederichs S.
Myacheva K, et al.
Cancer Lett. 2023 Jan 1;552:215958. doi: 10.1016/j.canlet.2022.215958. Epub 2022 Oct 14.
Cancer Lett. 2023.
PMID: 36252816
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Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.
Korkmaz G, Lopes R, Ugalde AP, Nevedomskaya E, Han R, Myacheva K, Zwart W, Elkon R, Agami R.
Korkmaz G, et al. Among authors: myacheva k.
Nat Biotechnol. 2016 Feb;34(2):192-8. doi: 10.1038/nbt.3450. Epub 2016 Jan 11.
Nat Biotechnol. 2016.
PMID: 26751173
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Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment.
Pelos G, Riester M, Pal J, Myacheva K, Moneke I, Rotondo JC, Lübbert M, Diederichs S.
Pelos G, et al. Among authors: myacheva k.
Int J Cancer. 2024 Mar 15;154(6):1029-1042. doi: 10.1002/ijc.34783. Epub 2023 Nov 10.
Int J Cancer. 2024.
PMID: 37947765
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