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Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease.
Del Balzo U, Signore PE, Walkinshaw G, Seeley TW, Brenner MC, Wang Q, Guo G, Arend MP, Flippin LA, Chow FA, Gervasi DC, Kjaergaard CH, Langsetmo I, Guenzler V, Liu DY, Klaus SJ, Lin A, Neff TB. Del Balzo U, et al. Among authors: kjaergaard ch. J Pharmacol Exp Ther. 2020 Aug;374(2):342-353. doi: 10.1124/jpet.120.265181. Epub 2020 Jun 2. J Pharmacol Exp Ther. 2020. PMID: 32487538
Spectroscopic and computational insight into the activation of O2 by the mononuclear Cu center in polysaccharide monooxygenases.
Kjaergaard CH, Qayyum MF, Wong SD, Xu F, Hemsworth GR, Walton DJ, Young NA, Davies GJ, Walton PH, Johansen KS, Hodgson KO, Hedman B, Solomon EI. Kjaergaard CH, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8797-802. doi: 10.1073/pnas.1408115111. Epub 2014 Jun 2. Proc Natl Acad Sci U S A. 2014. PMID: 24889637 Free PMC article.
Copper active sites in biology.
Solomon EI, Heppner DE, Johnston EM, Ginsbach JW, Cirera J, Qayyum M, Kieber-Emmons MT, Kjaergaard CH, Hadt RG, Tian L. Solomon EI, et al. Among authors: kjaergaard ch. Chem Rev. 2014 Apr 9;114(7):3659-853. doi: 10.1021/cr400327t. Epub 2014 Mar 3. Chem Rev. 2014. PMID: 24588098 Free PMC article. Review. No abstract available.
Spectroscopic and crystallographic characterization of "alternative resting" and "resting oxidized" enzyme forms of bilirubin oxidase: implications for activity and electrochemical behavior of multicopper oxidases.
Kjaergaard CH, Durand F, Tasca F, Qayyum MF, Kauffmann B, Gounel S, Suraniti E, Hodgson KO, Hedman B, Mano N, Solomon EI. Kjaergaard CH, et al. J Am Chem Soc. 2012 Mar 28;134(12):5548-51. doi: 10.1021/ja211872j. Epub 2012 Mar 21. J Am Chem Soc. 2012. PMID: 22413777 Free PMC article.
14 results