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Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells.
Gonzalez-Sanchez L, Cobos-Fernandez MA, Lopez-Nieva P, Villa-Morales M, Stamatakis K, Cuezva JM, Marin-Rubio JL, Vazquez-Dominguez I, Gonzalez-Vasconcellos I, Salido E, Llamas P, Lopez-Lorenzo JL, Santos J, Fernandez-Piqueras J. Gonzalez-Sanchez L, et al. Among authors: cobos fernandez ma. Carcinogenesis. 2020 Aug 12;41(8):1113-1122. doi: 10.1093/carcin/bgz185. Carcinogenesis. 2020. PMID: 31734690 Free article.
Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.
Roncero AM, López-Nieva P, Cobos-Fernández MA, Villa-Morales M, González-Sánchez L, López-Lorenzo JL, Llamas P, Ayuso C, Rodríguez-Pinilla SM, Arriba MC, Piris MA, Fernández-Navarro P, Fernández AF, Fraga MF, Santos J, Fernández-Piqueras J. Roncero AM, et al. Leukemia. 2016 Jan;30(1):94-103. doi: 10.1038/leu.2015.202. Epub 2015 Jul 28. Leukemia. 2016. PMID: 26216197 Free PMC article.
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas.
López-Nieva P, Fernández-Navarro P, Vaquero-Lorenzo C, Villa-Morales M, Graña-Castro O, Cobos-Fernández MÁ, López-Lorenzo JL, Llamas P, González-Sanchez L, Sastre I, Pollan M, Malumbres M, Santos J, Fernández-Piqueras J. López-Nieva P, et al. BMC Cancer. 2018 Apr 16;18(1):430. doi: 10.1186/s12885-018-4304-y. BMC Cancer. 2018. PMID: 29661169 Free PMC article.
Downregulation of specific FBXW7 isoforms with differential effects in T-cell lymphoblastic lymphoma.
Vázquez-Domínguez I, González-Sánchez L, López-Nieva P, Fernández-Navarro P, Villa-Morales M, Cobos-Fernández MÁ, Sastre I, F Fraga M, F Fernández A, Malumbres M, Salazar-Roa M, Graña-Castro O, Santos J, Llamas P, López-Lorenzo JL, Fernández-Piqueras J. Vázquez-Domínguez I, et al. Among authors: cobos fernandez ma. Oncogene. 2019 Jun;38(23):4620-4636. doi: 10.1038/s41388-019-0746-1. Epub 2019 Feb 11. Oncogene. 2019. PMID: 30742097
Detection of novel fusion-transcripts by RNA-Seq in T-cell lymphoblastic lymphoma.
López-Nieva P, Fernández-Navarro P, Graña-Castro O, Andrés-León E, Santos J, Villa-Morales M, Cobos-Fernández MÁ, González-Sánchez L, Malumbres M, Salazar-Roa M, Fernández-Piqueras J. López-Nieva P, et al. Among authors: cobos fernandez ma. Sci Rep. 2019 Mar 26;9(1):5179. doi: 10.1038/s41598-019-41675-3. Sci Rep. 2019. PMID: 30914738 Free PMC article.
The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data.
Fernández-Navarro P, López-Nieva P, Piñeiro-Yañez E, Carreño-Tarragona G, Martinez-López J, Sánchez Pérez R, Aroca Á, Al-Shahrour F, Cobos-Fernández MÁ, Fernández-Piqueras J. Fernández-Navarro P, et al. Among authors: cobos fernandez ma. BMC Cancer. 2019 Oct 26;19(1):1005. doi: 10.1186/s12885-019-6209-9. BMC Cancer. 2019. PMID: 31655559 Free PMC article.
More Insights on the Use of γ-Secretase Inhibitors in Cancer Treatment.
López-Nieva P, González-Sánchez L, Cobos-Fernández MÁ, Córdoba R, Santos J, Fernández-Piqueras J. López-Nieva P, et al. Among authors: cobos fernandez ma. Oncologist. 2021 Feb;26(2):e298-e305. doi: 10.1002/onco.13595. Epub 2020 Nov 26. Oncologist. 2021. PMID: 33191568 Free PMC article.
Patterns of Differentially Expressed circRNAs in Human Thymocytes.
López-Nieva P, Fernández-Navarro P, Cobos-Fernández MÁ, González-Vasconcellos I, Sánchez Pérez R, Aroca Á, Fernández-Piqueras J, Santos J. López-Nieva P, et al. Among authors: cobos fernandez ma. Noncoding RNA. 2022 Mar 30;8(2):26. doi: 10.3390/ncrna8020026. Noncoding RNA. 2022. PMID: 35447889 Free PMC article.
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