Claridge TDW - Search Results

1

Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid.

Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey DJ, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley JA, Russell AJ, Tinsley JM, Weaver R, Wilkinson IVL, Willis NJ, Wilson FX, Wynne GM. Chatzopoulou M, et al. Among authors: claridge tdw. J Med Chem. 2020 Mar 12;63(5):2547-2556. doi: 10.1021/acs.jmedchem.9b01547. Epub 2019 Oct 25. J Med Chem. 2020. PMID: 31599580

2

Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.

Madikane VE, Bhakta S, Russell AJ, Campbell WE, Claridge TD, Elisha BG, Davies SG, Smith P, Sim E. Madikane VE, et al. Bioorg Med Chem. 2007 May 15;15(10):3579-86. doi: 10.1016/j.bmc.2007.02.011. Epub 2007 Feb 11. Bioorg Med Chem. 2007. PMID: 17368035

3

Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol.

Aciro C, Claridge TD, Davies SG, Roberts PM, Russell AJ, Thomson JE. Aciro C, et al. Org Biomol Chem. 2008 Oct 21;6(20):3751-61. doi: 10.1039/b808811j. Epub 2008 Aug 20. Org Biomol Chem. 2008. PMID: 18843405

4

"Pure by NMR"?

Claridge TD, Davies SG, Polywka ME, Roberts PM, Russell AJ, Savory ED, Smith AD. Claridge TD, et al. Org Lett. 2008 Dec 4;10(23):5433-6. doi: 10.1021/ol802211p. Org Lett. 2008. PMID: 18975956

5

Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.

Claridge TD, Davies SG, Lee JA, Nicholson RL, Roberts PM, Russell AJ, Smith AD, Toms SM. Claridge TD, et al. Org Lett. 2008 Dec 4;10(23):5437-40. doi: 10.1021/ol802212e. Org Lett. 2008. PMID: 18975957

6

Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions.

Leung IK, Flashman E, Yeoh KK, Schofield CJ, Claridge TD. Leung IK, et al. J Med Chem. 2010 Jan 28;53(2):867-75. doi: 10.1021/jm901537q. J Med Chem. 2010. PMID: 20025281

7

Ammonium-directed olefinic epoxidation: kinetic and mechanistic insights.

Brennan MB, Claridge TD, Compton RG, Davies SG, Fletcher AM, Henstridge MC, Hewings DS, Kurosawa W, Lee JA, Roberts PM, Schoonen AK, Thomson JE. Brennan MB, et al. J Org Chem. 2012 Sep 7;77(17):7241-61. doi: 10.1021/jo3010556. Epub 2012 Aug 13. J Org Chem. 2012. PMID: 22827448

8

Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.

Leung IK, Demetriades M, Hardy AP, Lejeune C, Smart TJ, Szöllössi A, Kawamura A, Schofield CJ, Claridge TD. Leung IK, et al. J Med Chem. 2013 Jan 24;56(2):547-55. doi: 10.1021/jm301583m. Epub 2013 Jan 4. J Med Chem. 2013. PMID: 23234607 Free PMC article.

9

γ-Butyrobetaine hydroxylase catalyses a Stevens type rearrangement.

Henry L, Leung IK, Claridge TD, Schofield CJ. Henry L, et al. Bioorg Med Chem Lett. 2012 Aug 1;22(15):4975-8. doi: 10.1016/j.bmcl.2012.06.024. Epub 2012 Jun 16. Bioorg Med Chem Lett. 2012. PMID: 22765904

10

Monitoring protein-metal binding by ¹⁹F NMR - a case study with the New Delhi metallo-β-lactamase 1.

Rydzik AM, Brem J, Chandler SA, Benesch JLP, Claridge TDW, Schofield CJ. Rydzik AM, et al. Among authors: claridge tdw. RSC Med Chem. 2020 Feb 21;11(3):387-391. doi: 10.1039/c9md00416e. eCollection 2020 Mar 1. RSC Med Chem. 2020. PMID: 33479644 Free PMC article.

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