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Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides.
Quintana-Espinoza P, García-Luis J, Amesty A, Martín-Rodríguez P, Lorenzo-Castrillejo I, Ravelo AG, Fernández-Pérez L, Machín F, Estévez-Braun A. Quintana-Espinoza P, et al. Among authors: lorenzo castrillejo i. Bioorg Med Chem. 2013 Nov 1;21(21):6484-95. doi: 10.1016/j.bmc.2013.08.039. Epub 2013 Aug 29. Bioorg Med Chem. 2013. PMID: 24054489
Multiplex PCR assay for identification of six different Staphylococcus spp. and simultaneous detection of methicillin and mupirocin resistance.
Campos-Peña E, Martín-Nuñez E, Pulido-Reyes G, Martín-Padrón J, Caro-Carrillo E, Donate-Correa J, Lorenzo-Castrillejo I, Alcoba-Flórez J, Machín F, Méndez-Alvarez S. Campos-Peña E, et al. Among authors: lorenzo castrillejo i. J Clin Microbiol. 2014 Jul;52(7):2698-701. doi: 10.1128/JCM.00918-14. Epub 2014 May 14. J Clin Microbiol. 2014. PMID: 24829244 Free PMC article.
Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage.
Ramos-Pérez C, Lorenzo-Castrillejo I, Quevedo O, García-Luis J, Matos-Perdomo E, Medina-Coello C, Estévez-Braun A, Machín F. Ramos-Pérez C, et al. Among authors: lorenzo castrillejo i. Biochem Pharmacol. 2014 Nov 15;92(2):206-19. doi: 10.1016/j.bcp.2014.09.006. Epub 2014 Sep 21. Biochem Pharmacol. 2014. PMID: 25241291
5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation.
Quintana-Espinoza P, Martín-Acosta P, Amesty Á, Martín-Rodríguez P, Lorenzo-Castrillejo I, Fernández-Pérez L, Machín F, Estévez-Braun A. Quintana-Espinoza P, et al. Among authors: lorenzo castrillejo i. Bioorg Med Chem. 2017 Mar 15;25(6):1976-1983. doi: 10.1016/j.bmc.2017.02.024. Epub 2017 Feb 13. Bioorg Med Chem. 2017. PMID: 28233678
Lawsone, Juglone, and β-Lapachone Derivatives with Enhanced Mitochondrial-Based Toxicity.
Anaissi-Afonso L, Oramas-Royo S, Ayra-Plasencia J, Martín-Rodríguez P, García-Luis J, Lorenzo-Castrillejo I, Fernández-Pérez L, Estévez-Braun A, Machín F. Anaissi-Afonso L, et al. Among authors: lorenzo castrillejo i. ACS Chem Biol. 2018 Aug 17;13(8):1950-1957. doi: 10.1021/acschembio.8b00306. Epub 2018 Jun 15. ACS Chem Biol. 2018. PMID: 29878754
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