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Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages.
Howes A, Taubert C, Blankley S, Spink N, Wu X, Graham CM, Zhao J, Saraiva M, Ricciardi-Castagnoli P, Bancroft GJ, O'Garra A. Howes A, et al. Among authors: graham cm. J Immunol. 2016 Oct 1;197(7):2838-53. doi: 10.4049/jimmunol.1501923. Epub 2016 Aug 22. J Immunol. 2016. PMID: 27549173 Free PMC article.
The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease.
Conejero L, Potempa K, Graham CM, Spink N, Blankley S, Salguero FJ, Pankla-Sranujit R, Khaenam P, Banchereau JF, Pascual V, Chaussabel D, Lertmemongkolchai G, O'Garra A, Bancroft GJ. Conejero L, et al. Among authors: graham cm. J Immunol. 2015 Oct 1;195(7):3248-3261. doi: 10.4049/jimmunol.1500641. Epub 2015 Aug 26. J Immunol. 2015. PMID: 26311902 Free PMC article.
TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production.
McNab FW, Ewbank J, Rajsbaum R, Stavropoulos E, Martirosyan A, Redford PS, Wu X, Graham CM, Saraiva M, Tsichlis P, Chaussabel D, Ley SC, O'Garra A. McNab FW, et al. Among authors: graham cm. J Immunol. 2013 Aug 15;191(4):1732-43. doi: 10.4049/jimmunol.1300146. Epub 2013 Jul 10. J Immunol. 2013. PMID: 23842752 Free PMC article.
Systems approaches to studying the immune response in tuberculosis.
Berry MP, Blankley S, Graham CM, Bloom CI, O'Garra A. Berry MP, et al. Among authors: graham cm. Curr Opin Immunol. 2013 Oct;25(5):579-87. doi: 10.1016/j.coi.2013.08.003. Epub 2013 Sep 7. Curr Opin Immunol. 2013. PMID: 24021227 Review.
Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling.
Pitt JM, Blankley S, Potempa K, Graham CM, Moreira-Teixeira L, McNab FW, Howes A, Stavropoulos E, Pascual V, Banchereau J, Chaussabel D, O'Garra A. Pitt JM, et al. Among authors: graham cm. PLoS One. 2016 Feb 26;11(2):e0150251. doi: 10.1371/journal.pone.0150251. eCollection 2016. PLoS One. 2016. PMID: 26918359 Free PMC article.
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis.
Moreira-Teixeira L, Tabone O, Graham CM, Singhania A, Stavropoulos E, Redford PS, Chakravarty P, Priestnall SL, Suarez-Bonnet A, Herbert E, Mayer-Barber KD, Sher A, Fonseca KL, Sousa J, Cá B, Verma R, Haldar P, Saraiva M, O'Garra A. Moreira-Teixeira L, et al. Among authors: graham cm. Nat Immunol. 2020 Apr;21(4):464-476. doi: 10.1038/s41590-020-0610-z. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205882 Free PMC article.
Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ, Moffatt MF, O'Garra A, Openshaw PJM; MOSAIC Investigators. Dunning J, et al. Among authors: graham cm. Nat Immunol. 2018 Jun;19(6):625-635. doi: 10.1038/s41590-018-0111-5. Epub 2018 May 18. Nat Immunol. 2018. PMID: 29777224 Free PMC article.
Author Correction: Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.
Dunning J, Blankley S, Hoang LT, Cox M, Graham CM, James PL, Bloom CI, Chaussabel D, Banchereau J, Brett SJ; MOSAIC Investigators; Moffatt MF, O'Garra A, Openshaw PJM. Dunning J, et al. Among authors: graham cm. Nat Immunol. 2019 Mar;20(3):373. doi: 10.1038/s41590-019-0328-y. Nat Immunol. 2019. PMID: 30728492 Free article.
Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases.
Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, Frickel E, Sesay AK, Priestnall SL, Herbert E, Ioannou M, Wang Q, Humphreys IR, Dodd J, Openshaw PJM, Mayer-Barber KD, Jankovic D, Sher A, Lloyd CM, Baldwin N, Chaussabel D, Papayannopoulos V, Wack A, Banchereau JF, Pascual VM, O'Garra A. Singhania A, et al. Among authors: graham cm. Nat Commun. 2019 Jun 28;10(1):2887. doi: 10.1038/s41467-019-10601-6. Nat Commun. 2019. PMID: 31253760 Free PMC article.
85 results