Ascher DB - Search Results

1

Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins.

Coelho MB, Ascher DB, Gooding C, Lang E, Maude H, Turner D, Llorian M, Pires DE, Attig J, Smith CW. Coelho MB, et al. Among authors: ascher db. Biochem Soc Trans. 2016 Aug 15;44(4):1058-65. doi: 10.1042/BST20160080. Biochem Soc Trans. 2016. PMID: 27528752 Review.

2

mCSM: predicting the effects of mutations in proteins using graph-based signatures.

Pires DE, Ascher DB, Blundell TL. Pires DE, et al. Among authors: ascher db. Bioinformatics. 2014 Feb 1;30(3):335-42. doi: 10.1093/bioinformatics/btt691. Epub 2013 Nov 26. Bioinformatics. 2014. PMID: 24281696 Free PMC article.

3

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach.

Pires DE, Ascher DB, Blundell TL. Pires DE, et al. Among authors: ascher db. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W314-9. doi: 10.1093/nar/gku411. Epub 2014 May 14. Nucleic Acids Res. 2014. PMID: 24829462 Free PMC article.

4

Platinum: a database of experimentally measured effects of mutations on structurally defined protein-ligand complexes.

Pires DE, Blundell TL, Ascher DB. Pires DE, et al. Among authors: ascher db. Nucleic Acids Res. 2015 Jan;43(Database issue):D387-91. doi: 10.1093/nar/gku966. Epub 2014 Oct 16. Nucleic Acids Res. 2015. PMID: 25324307 Free PMC article.

5

Analysis of HGD Gene Mutations in Patients with Alkaptonuria from the United Kingdom: Identification of Novel Mutations.

Usher JL, Ascher DB, Pires DE, Milan AM, Blundell TL, Ranganath LR. Usher JL, et al. Among authors: ascher db. JIMD Rep. 2015;24:3-11. doi: 10.1007/8904_2014_380. Epub 2015 Feb 15. JIMD Rep. 2015. PMID: 25681086 Free PMC article.

6

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures.

Pires DE, Blundell TL, Ascher DB. Pires DE, et al. Among authors: ascher db. J Med Chem. 2015 May 14;58(9):4066-72. doi: 10.1021/acs.jmedchem.5b00104. Epub 2015 Apr 22. J Med Chem. 2015. PMID: 25860834 Free PMC article.

7

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma.

Jafri M, Wake NC, Ascher DB, Pires DE, Gentle D, Morris MR, Rattenberry E, Simpson MA, Trembath RC, Weber A, Woodward ER, Donaldson A, Blundell TL, Latif F, Maher ER. Jafri M, et al. Among authors: ascher db. Cancer Discov. 2015 Jul;5(7):723-9. doi: 10.1158/2159-8290.CD-14-1096. Epub 2015 Apr 14. Cancer Discov. 2015. PMID: 25873077

8

In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity.

Pires DE, Chen J, Blundell TL, Ascher DB. Pires DE, et al. Among authors: ascher db. Sci Rep. 2016 Jan 22;6:19848. doi: 10.1038/srep19848. Sci Rep. 2016. PMID: 26797105 Free PMC article.

9

Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance.

Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG. Phelan J, et al. Among authors: ascher db. BMC Med. 2016 Mar 23;14:31. doi: 10.1186/s12916-016-0575-9. BMC Med. 2016. PMID: 27005572 Free PMC article.

10

CSM-lig: a web server for assessing and comparing protein-small molecule affinities.

Pires DE, Ascher DB. Pires DE, et al. Among authors: ascher db. Nucleic Acids Res. 2016 Jul 8;44(W1):W557-61. doi: 10.1093/nar/gkw390. Epub 2016 May 5. Nucleic Acids Res. 2016. PMID: 27151202 Free PMC article.

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