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Biological evaluation and molecular docking studies of AA3052, a compound containing a μ-selective opioid peptide agonist DALDA and d-Phe-Phe-d-Phe-Leu-Leu-NH2, a substance P analogue.
Kowalczyk A, Kleczkowska P, Rękawek M, Kulik K, Lesniak A, Erdei A, Borics A, Martin C, Pawlik K, Lipkowski AW, Benyhe S, Makulska-Nowak H, Ballet S, Bujalska-Zadrozny M. Kowalczyk A, et al. Among authors: ballet s. Eur J Pharm Sci. 2016 Oct 10;93:11-20. doi: 10.1016/j.ejps.2016.07.009. Epub 2016 Jul 14. Eur J Pharm Sci. 2016. PMID: 27423260
Synthesis, biological evaluation, and automated docking of constrained analogues of the opioid peptide H-Dmt-D-Ala-Phe-Gly-NH₂ using the 4- or 5-methyl substituted 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one scaffold.
De Wachter R, de Graaf C, Keresztes A, Vandormael B, Ballet S, Tóth G, Rognan D, Tourwé D. De Wachter R, et al. Among authors: ballet s. J Med Chem. 2011 Oct 13;54(19):6538-47. doi: 10.1021/jm2003574. Epub 2011 Sep 14. J Med Chem. 2011. PMID: 21870874
In vivo antinociception of potent mu opioid agonist tetrapeptide analogues and comparison with a compact opioid agonist-neurokinin 1 receptor antagonist chimera.
Guillemyn K, Kleczkowska P, Novoa A, Vandormael B, Van den Eynde I, Kosson P, Asim MF, Schiller PW, Spetea M, Lipkowski AW, Tourwé D, Ballet S. Guillemyn K, et al. Among authors: ballet s. Mol Brain. 2012 Jan 30;5:4. doi: 10.1186/1756-6606-5-4. Mol Brain. 2012. PMID: 22289619 Free PMC article.
Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.
Novoa A, Van Dorpe S, Wynendaele E, Spetea M, Bracke N, Stalmans S, Betti C, Chung NN, Lemieux C, Zuegg J, Cooper MA, Tourwé D, De Spiegeleer B, Schiller PW, Ballet S. Novoa A, et al. Among authors: ballet s. J Med Chem. 2012 Nov 26;55(22):9549-61. doi: 10.1021/jm3008079. Epub 2012 Nov 12. J Med Chem. 2012. PMID: 23102273 Free PMC article.
Hybrid opioid/non-opioid ligands in pain research.
Kleczkowska P, Lipkowski AW, Tourwé D, Ballet S. Kleczkowska P, et al. Among authors: ballet s. Curr Pharm Des. 2013;19(42):7435-50. doi: 10.2174/138161281942140105165646. Curr Pharm Des. 2013. PMID: 23448481 Review.
176 results