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A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.
Martel CM, Parker JE, Bader O, Weig M, Gross U, Warrilow AG, Kelly DE, Kelly SL. Martel CM, et al. Among authors: bader o. Antimicrob Agents Chemother. 2010 Sep;54(9):3578-83. doi: 10.1128/AAC.00303-10. Epub 2010 Jun 14. Antimicrob Agents Chemother. 2010. PMID: 20547793 Free PMC article.
Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B.
Hull CM, Parker JE, Bader O, Weig M, Gross U, Warrilow AG, Kelly DE, Kelly SL. Hull CM, et al. Among authors: bader o. Antimicrob Agents Chemother. 2012 Aug;56(8):4223-32. doi: 10.1128/AAC.06253-11. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615281 Free PMC article.
164 results