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Bridging disulfides for stable and defined antibody drug conjugates.
Bioconjug Chem. 2014 Jun 18;25(6):1124-36. doi: 10.1021/bc500148x. Epub 2014 May 23.
Bioconjug Chem. 2014.
PMID: 24791606
Site-specific PEGylation at histidine tags.
Cong Y, Pawlisz E, Bryant P, Balan S, Laurine E, Tommasi R, Singh R, Dubey S, Peciak K, Bird M, Sivasankar A, Swierkosz J, Muroni M, Heidelberger S, Farys M, Khayrzad F, Edwards J, Badescu G, Hodgson I, Heise C, Somavarapu S, Liddell J, Powell K, Zloh M, Choi JW, Godwin A, Brocchini S.
Cong Y, et al. Among authors: farys m.
Bioconjug Chem. 2012 Feb 15;23(2):248-63. doi: 10.1021/bc200530x. Epub 2012 Feb 6.
Bioconjug Chem. 2012.
PMID: 22243664
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A new reagent for stable thiol-specific conjugation.
Badescu G, Bryant P, Swierkosz J, Khayrzad F, Pawlisz E, Farys M, Cong Y, Muroni M, Rumpf N, Brocchini S, Godwin A.
Badescu G, et al. Among authors: farys m.
Bioconjug Chem. 2014 Mar 19;25(3):460-9. doi: 10.1021/bc400245v. Epub 2014 Feb 11.
Bioconjug Chem. 2014.
PMID: 24512057
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Causes of Industrial Protein A Column Degradation, Explored Using Raman Spectroscopy.
Beattie JW, Istrate A, Lu A, Marshall C, Rowland-Jones RC, Farys M, Kazarian SG, Byrne B.
Beattie JW, et al. Among authors: farys m.
Anal Chem. 2022 Nov 15;94(45):15703-15710. doi: 10.1021/acs.analchem.2c03063. Epub 2022 Nov 1.
Anal Chem. 2022.
PMID: 36318727
Free PMC article.
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Isotype dependent on-column non-reversible aggregation of monoclonal antibodies.
Farys M, Gibson D, Lewis AP, Lewis W, Kucia-Tran R.
Farys M, et al.
Biotechnol Bioeng. 2018 May;115(5):1279-1287. doi: 10.1002/bit.26547. Epub 2018 Feb 4.
Biotechnol Bioeng. 2018.
PMID: 29315494
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Insight into purification of monoclonal antibodies in industrial columns via studies of Protein A binding capacity by in situ ATR-FTIR spectroscopy.
Beattie JW, Rowland-Jones RC, Farys M, Tran R, Kazarian SG, Byrne B.
Beattie JW, et al. Among authors: farys m.
Analyst. 2021 Aug 9;146(16):5177-5185. doi: 10.1039/d1an00985k.
Analyst. 2021.
PMID: 34296229
Free PMC article.
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Application of Raman Spectroscopy to Dynamic Binding Capacity Analysis.
Beattie JW, Rowland-Jones RC, Farys M, Bettany H, Hilton D, Kazarian SG, Byrne B.
Beattie JW, et al. Among authors: farys m.
Appl Spectrosc. 2023 Dec;77(12):1393-1400. doi: 10.1177/00037028231210293. Epub 2023 Nov 1.
Appl Spectrosc. 2023.
PMID: 37908083
Free PMC article.
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