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Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.
McCoy LE, Groppelli E, Blanchetot C, de Haard H, Verrips T, Rutten L, Weiss RA, Jolly C. McCoy LE, et al. Among authors: verrips t. Retrovirology. 2014 Oct 2;11:83. doi: 10.1186/s12977-014-0083-y. Retrovirology. 2014. PMID: 25700025 Free PMC article.
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1.
McCoy LE, Rutten L, Frampton D, Anderson I, Granger L, Bashford-Rogers R, Dekkers G, Strokappe NM, Seaman MS, Koh W, Grippo V, Kliche A, Verrips T, Kellam P, Fassati A, Weiss RA. McCoy LE, et al. Among authors: verrips t. PLoS Pathog. 2014 Dec 18;10(12):e1004552. doi: 10.1371/journal.ppat.1004552. eCollection 2014 Dec. PLoS Pathog. 2014. PMID: 25522326 Free PMC article.
Llama antibody fragments with cross-subtype human immunodeficiency virus type 1 (HIV-1)-neutralizing properties and high affinity for HIV-1 gp120.
Forsman A, Beirnaert E, Aasa-Chapman MM, Hoorelbeke B, Hijazi K, Koh W, Tack V, Szynol A, Kelly C, McKnight A, Verrips T, de Haard H, Weiss RA. Forsman A, et al. Among authors: verrips t. J Virol. 2008 Dec;82(24):12069-81. doi: 10.1128/JVI.01379-08. Epub 2008 Oct 8. J Virol. 2008. PMID: 18842738 Free PMC article.
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells.
Jähnichen S, Blanchetot C, Maussang D, Gonzalez-Pajuelo M, Chow KY, Bosch L, De Vrieze S, Serruys B, Ulrichts H, Vandevelde W, Saunders M, De Haard HJ, Schols D, Leurs R, Vanlandschoot P, Verrips T, Smit MJ. Jähnichen S, et al. Among authors: verrips t. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20565-70. doi: 10.1073/pnas.1012865107. Epub 2010 Nov 8. Proc Natl Acad Sci U S A. 2010. PMID: 21059953 Free PMC article.
Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.
McCoy LE, Quigley AF, Strokappe NM, Bulmer-Thomas B, Seaman MS, Mortier D, Rutten L, Chander N, Edwards CJ, Ketteler R, Davis D, Verrips T, Weiss RA. McCoy LE, et al. Among authors: verrips t. J Exp Med. 2012 Jun 4;209(6):1091-103. doi: 10.1084/jem.20112655. Epub 2012 May 28. J Exp Med. 2012. PMID: 22641382 Free PMC article.
Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.
Zhou T, Chen L, Gorman J, Wang S, Kwon YD, Lin BC, Louder MK, Rawi R, Stancofski ED, Yang Y, Zhang B, Quigley AF, McCoy LE, Rutten L, Verrips T, Weiss RA; VRC Production Program; Doria-Rose NA, Shapiro L, Kwong PD. Zhou T, et al. Among authors: verrips t. Structure. 2022 Jun 2;30(6):862-875.e4. doi: 10.1016/j.str.2022.03.012. Epub 2022 Apr 11. Structure. 2022. PMID: 35413243 Free PMC article.
44 results