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Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.
Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM. Juvekar A, et al. Among authors: burga ln. Cancer Discov. 2012 Nov;2(11):1048-63. doi: 10.1158/2159-8290.CD-11-0336. Epub 2012 Aug 22. Cancer Discov. 2012. PMID: 22915751 Free PMC article.
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.
Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG. Israelsen WJ, et al. Among authors: burga ln. Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025. Cell. 2013. PMID: 24120138 Free PMC article.
Cryo-Electron Microscopy Structure of Seneca Valley Virus Procapsid.
Strauss M, Jayawardena N, Sun E, Easingwood RA, Burga LN, Bostina M. Strauss M, et al. Among authors: burga ln. J Virol. 2018 Feb 26;92(6):e01927-17. doi: 10.1128/JVI.01927-17. Print 2018 Mar 15. J Virol. 2018. PMID: 29263256 Free PMC article.
Developing Picornaviruses for Cancer Therapy.
McCarthy C, Jayawardena N, Burga LN, Bostina M. McCarthy C, et al. Among authors: burga ln. Cancers (Basel). 2019 May 16;11(5):685. doi: 10.3390/cancers11050685. Cancers (Basel). 2019. PMID: 31100962 Free PMC article. Review.
19 results