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Pradimicin S, a highly soluble nonpeptidic small-size carbohydrate-binding antibiotic, is an anti-HIV drug lead for both microbicidal and systemic use.
Balzarini J, François KO, Van Laethem K, Hoorelbeke B, Renders M, Auwerx J, Liekens S, Oki T, Igarashi Y, Schols D. Balzarini J, et al. Among authors: hoorelbeke b. Antimicrob Agents Chemother. 2010 Apr;54(4):1425-35. doi: 10.1128/AAC.01347-09. Epub 2010 Jan 4. Antimicrob Agents Chemother. 2010. PMID: 20047920 Free PMC article.
The lantibiotic peptide labyrinthopeptin A1 demonstrates broad anti-HIV and anti-HSV activity with potential for microbicidal applications.
Férir G, Petrova MI, Andrei G, Huskens D, Hoorelbeke B, Snoeck R, Vanderleyden J, Balzarini J, Bartoschek S, Brönstrup M, Süssmuth RD, Schols D. Férir G, et al. Among authors: hoorelbeke b. PLoS One. 2013 May 28;8(5):e64010. doi: 10.1371/journal.pone.0064010. Print 2013. PLoS One. 2013. PMID: 23724015 Free PMC article.
Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides.
Di Fabio G, D'Onofrio J, Chiapparelli M, Hoorelbeke B, Montesarchio D, Balzarini J, De Napoli L. Di Fabio G, et al. Among authors: hoorelbeke b. Chem Commun (Camb). 2011 Feb 28;47(8):2363-5. doi: 10.1039/c0cc04751a. Epub 2010 Dec 16. Chem Commun (Camb). 2011. PMID: 21305065 Free article.
28 results