Findlay J - Search Results

1

Synthesis, binding studies and in vivo biological evaluation of novel non-peptide antihypertensive analogues.

Mavromoustakos T, Moutevelis-Minakakis P, Kokotos CG, Kontogianni P, Politi A, Zoumpoulakis P, Findlay J, Cox A, Balmforth A, Zoga A, Iliodromitis E. Mavromoustakos T, et al. Among authors: findlay j. Bioorg Med Chem. 2006 Jul 1;14(13):4353-60. doi: 10.1016/j.bmc.2006.02.044. Epub 2006 Mar 20. Bioorg Med Chem. 2006. PMID: 16546395

2

Novel selective and potent 5-HT reuptake inhibitors with 5-HT1D antagonist activity: chemistry and pharmacological evaluation of a series of thienopyran derivatives.

Torrado A, Lamas C, Agejas J, Jiménez A, Diaz N, Gilmore J, Boot J, Findlay J, Hayhurst L, Wallace L, Broadmore R, Tomlinson R. Torrado A, et al. Among authors: findlay j. Bioorg Med Chem. 2004 Oct 15;12(20):5277-95. doi: 10.1016/j.bmc.2004.07.059. Bioorg Med Chem. 2004. PMID: 15388156

3

Naphthyl piperazines with dual activity as 5-HT1D antagonists and 5-HT reuptake inhibitors.

Bueno AB, Gilmore J, Boot J, Broadmore R, Cooper J, Findlay J, Hayhurst L, Marcos A, Montero C, Mitchell S, Timms G, Tomlinson R, Wallace L, Walton L. Bueno AB, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3344-8. doi: 10.1016/j.bmcl.2007.03.101. Epub 2007 Apr 5. Bioorg Med Chem Lett. 2007. PMID: 17434731

4

Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.

Boot J, Cases M, Clark BP, Findlay J, Gallagher PT, Hayhurst L, Man T, Montalbetti C, Rathmell RE, Rudyk H, Walter MW, Whatton M, Wood V. Boot J, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2005 Feb 1;15(3):699-703. doi: 10.1016/j.bmcl.2004.11.025. Bioorg Med Chem Lett. 2005. PMID: 15664840

5

Discovery of novel and selective tertiary alcohol containing inhibitors of the norepinephrine transporter.

Cases-Thomas MJ, Masters JJ, Walter MW, Campbell G, Haughton L, Gallagher PT, Dobson DR, Mancuso V, Bonnier B, Giard T, Defrance T, Vanmarsenille M, Ledgard A, White C, Ouwerkerk-Mahadevan S, Brunelle FJ, Dezutter NA, Herbots CA, Lienard JY, Findlay J, Hayhurst L, Boot J, Thompson LK, Hemrick-Luecke S. Cases-Thomas MJ, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2022-5. doi: 10.1016/j.bmcl.2005.12.061. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16413778

6

SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

Timms GH, Boot JR, Broadmore RJ, Carney SL, Cooper J, Findlay JD, Gilmore J, Mitchell S, Moore NA, Pullar I, Sanger GJ, Tomlinson R, Tree BB, Wedley S. Timms GH, et al. Among authors: findlay jd. Bioorg Med Chem Lett. 2004 May 17;14(10):2469-72. doi: 10.1016/j.bmcl.2004.03.003. Bioorg Med Chem Lett. 2004. PMID: 15109634

7

Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.

Boot JR, Brace G, Delatour CL, Dezutter N, Fairhurst J, Findlay J, Gallagher PT, Hoes I, Mahadevan S, Mitchell SN, Rathmell RE, Richards SJ, Simmonds RG, Wallace L, Whatton MA. Boot JR, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5395-9. doi: 10.1016/j.bmcl.2004.08.005. Bioorg Med Chem Lett. 2004. PMID: 15454233

8

Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake.

Bymaster FP, Beedle EE, Findlay J, Gallagher PT, Krushinski JH, Mitchell S, Robertson DW, Thompson DC, Wallace L, Wong DT. Bymaster FP, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4477-80. doi: 10.1016/j.bmcl.2003.08.079. Bioorg Med Chem Lett. 2003. PMID: 14643350

9

N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.

Boot JR, Boulet SL, Clark BP, Cases-Thomas MJ, Delhaye L, Diker K, Fairhurst J, Findlay J, Gallagher PT, Gilmore J, Harris JR, Masters JJ, Mitchell SN, Naik M, Simmonds RG, Smith SM, Richards SJ, Timms GH, Whatton MA, Wolfe CN, Wood VA. Boot JR, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2006 May 15;16(10):2714-8. doi: 10.1016/j.bmcl.2006.02.008. Epub 2006 Feb 23. Bioorg Med Chem Lett. 2006. PMID: 16497500

10

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors.

Beadle CD, Boot J, Camp NP, Dezutter N, Findlay J, Hayhurst L, Masters JJ, Penariol R, Walter MW. Beadle CD, et al. Among authors: findlay j. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4432-7. doi: 10.1016/j.bmcl.2005.07.038. Bioorg Med Chem Lett. 2005. PMID: 16137883

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