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High-resolution genomic profiles of human lung cancer.
Tonon G, Wong KK, Maulik G, Brennan C, Feng B, Zhang Y, Khatry DB, Protopopov A, You MJ, Aguirre AJ, Martin ES, Yang Z, Ji H, Chin L, Depinho RA. Tonon G, et al. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9625-30. doi: 10.1073/pnas.0504126102. Epub 2005 Jun 27. Proc Natl Acad Sci U S A. 2005. PMID: 15983384 Free PMC article.
K-ras activation generates an inflammatory response in lung tumors.
Ji H, Houghton AM, Mariani TJ, Perera S, Kim CB, Padera R, Tonon G, McNamara K, Marconcini LA, Hezel A, El-Bardeesy N, Bronson RT, Sugarbaker D, Maser RS, Shapiro SD, Wong KK. Ji H, et al. Among authors: tonon g. Oncogene. 2006 Mar 30;25(14):2105-12. doi: 10.1038/sj.onc.1209237. Oncogene. 2006. PMID: 16288213
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Carrasco DR, Tonon G, Huang Y, Zhang Y, Sinha R, Feng B, Stewart JP, Zhan F, Khatry D, Protopopova M, Protopopov A, Sukhdeo K, Hanamura I, Stephens O, Barlogie B, Anderson KC, Chin L, Shaughnessy JD Jr, Brennan C, Depinho RA. Carrasco DR, et al. Among authors: tonon g. Cancer Cell. 2006 Apr;9(4):313-25. doi: 10.1016/j.ccr.2006.03.019. Cancer Cell. 2006. PMID: 16616336 Free article.
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.
Podar K, Tonon G, Sattler M, Tai YT, Legouill S, Yasui H, Ishitsuka K, Kumar S, Kumar R, Pandite LN, Hideshima T, Chauhan D, Anderson KC. Podar K, et al. Among authors: tonon g. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19478-83. doi: 10.1073/pnas.0609329103. Epub 2006 Dec 12. Proc Natl Acad Sci U S A. 2006. PMID: 17164332 Free PMC article.
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis.
Carrasco DR, Sukhdeo K, Protopopova M, Sinha R, Enos M, Carrasco DE, Zheng M, Mani M, Henderson J, Pinkus GS, Munshi N, Horner J, Ivanova EV, Protopopov A, Anderson KC, Tonon G, DePinho RA. Carrasco DR, et al. Among authors: tonon g. Cancer Cell. 2007 Apr;11(4):349-60. doi: 10.1016/j.ccr.2007.02.015. Cancer Cell. 2007. PMID: 17418411 Free PMC article.
Moving toward individualized cancer therapies.
Tonon G, Anderson KC. Tonon G, et al. Clin Cancer Res. 2008 Aug 1;14(15):4682-4. doi: 10.1158/1078-0432.CCR-08-1134. Clin Cancer Res. 2008. PMID: 18676734 Review.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Among authors: tonon g. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
198 results