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Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target.
Roychowdhury T, Klarin D, Levin MG, Spin JM, Rhee YH, Deng A, Headley CA, Tsao NL, Gellatly C, Zuber V, Shen F, Hornsby WE, Laursen IH, Verma SS, Locke AE, Einarsson G, Thorleifsson G, Graham SE, Dikilitas O, Pattee JW, Judy RL, Pauls-Verges F, Nielsen JB, Wolford BN, Brumpton BM, Dilmé J, Peypoch O, Juscafresa LC, Edwards TL, Li D, Banasik K, Brunak S, Jacobsen RL, Garcia-Barrio MT, Zhang J, Rasmussen LM, Lee R, Handa A, Wanhainen A, Mani K, Lindholt JS, Obel LM, Strauss E, Oszkinis G, Nelson CP, Saxby KL, van Herwaarden JA, van der Laan SW, van Setten J, Camacho M, Davis FM, Wasikowski R, Tsoi LC, Gudjonsson JE, Eliason JL, Coleman DM, Henke PK, Ganesh SK, Chen YE, Guan W, Pankow JS, Pankratz N, Pedersen OB, Erikstrup C, Tang W, Hveem K, Gudbjartsson D, Gretarsdottir S, Thorsteinsdottir U, Holm H, Stefansson K, Ferreira MA, Baras A, Kullo IJ, Ritchie MD, Christensen AH, Iversen KK, Eldrup N, Sillesen H, Ostrowski SR, Bundgaard H, Ullum H, Burgess S, Gill D, Gallagher K, Sabater-Lleal M; DiscovEHR; Regeneron Genetics Center; UK Aneurysm Growth Study; DBDS Genomic Consortium; VA Million Veteran Program; Surakka I, Jones GT, Bown MJ, Tsao PS, Willer CJ, Damrauer SM. Roychowdhury T, et al. Among authors: van der laan sw. Nat Genet. 2023 Nov;55(11):1831-1842. doi: 10.1038/s41588-023-01510-y. Epub 2023 Oct 16. Nat Genet. 2023. PMID: 37845353 Free PMC article.
Lack of association between connexin40 polymorphisms and coronary artery disease.
Pfenniger A, van der Laan SW, Foglia B, Dunoyer-Geindre S, Haefliger JA, Winnik S, Mach F, Pasterkamp G, James RW, Kwak BR. Pfenniger A, et al. Among authors: van der laan sw. Atherosclerosis. 2012 May;222(1):148-53. doi: 10.1016/j.atherosclerosis.2012.01.050. Epub 2012 Feb 8. Atherosclerosis. 2012. PMID: 22405441
Captopril and the immune system.
Kallenberg CG, van der Laan S, de Zeeuw D. Kallenberg CG, et al. Lancet. 1981 Jul 11;2(8237):92. doi: 10.1016/s0140-6736(81)90441-4. Lancet. 1981. PMID: 6113464 No abstract available.
Platelet RNA modules point to coronary calcification in asymptomatic women with former preeclampsia.
Hartman RJG, Korporaal SJA, Mokry M, de Jager SCA, Meeuwsen JAL, van der Laan SW, Lansu NR, Zoet GA, Pasterkamp G, Urbanus RT, Hoefer IE, Franx A, Velthuis BK, van Rijn BB, den Ruijter HM; Queen of Hearts and CREW consortia. Hartman RJG, et al. Among authors: van der laan sw, van rijn bb. Atherosclerosis. 2019 Dec;291:114-121. doi: 10.1016/j.atherosclerosis.2019.10.009. Epub 2019 Oct 11. Atherosclerosis. 2019. PMID: 31706077
107 results