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Rhinoviruses usurp STING for replication.
Luteijn RD, van Kuppeveld FJM. Luteijn RD, et al. Among authors: van kuppeveld fjm. Nat Microbiol. 2022 May;7(5):605-606. doi: 10.1038/s41564-022-01117-9. Nat Microbiol. 2022. PMID: 35508718 No abstract available.
Cholesterol: fa(s)t-food for enterovirus genome replication.
Strating JR, van der Schaar HM, van Kuppeveld FJ. Strating JR, et al. Trends Microbiol. 2013 Nov;21(11):560-1. doi: 10.1016/j.tim.2013.09.007. Epub 2013 Oct 6. Trends Microbiol. 2013. PMID: 24103385 Free PMC article.
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878
The life cycle of non-polio enteroviruses and how to target it.
Baggen J, Thibaut HJ, Strating JRPM, van Kuppeveld FJM. Baggen J, et al. Among authors: van kuppeveld fjm. Nat Rev Microbiol. 2018 Jun;16(6):368-381. doi: 10.1038/s41579-018-0005-4. Nat Rev Microbiol. 2018. PMID: 29626210 Review.
Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association.
Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, van Vliet ALW, Dekker JG, van der Grein SG, Saucedo JG, Anand AA, Trellet ME, Bonvin AMJJ, Walter P, Heck AJR, de Groot RJ, van Kuppeveld FJM. Rabouw HH, et al. Among authors: van der grein sg, van kuppeveld fjm, van vliet alw. Nat Microbiol. 2020 Nov;5(11):1361-1373. doi: 10.1038/s41564-020-0759-0. Epub 2020 Jul 20. Nat Microbiol. 2020. PMID: 32690955
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses.
Grazia Martina M, Vicenti I, Bauer L, Crespan E, Rango E, Boccuto A, Olivieri N, Incerti M, Zwaagstra M, Allodi M, Bertoni S, Dreassi E, Zazzi M, van Kuppeveld FJM, Maga G, Radi M. Grazia Martina M, et al. Among authors: van kuppeveld fjm. ChemMedChem. 2021 Dec 6;16(23):3548-3552. doi: 10.1002/cmdc.202100483. Epub 2021 Sep 7. ChemMedChem. 2021. PMID: 34382337 Free PMC article.
Antiviral responses are shaped by heterogeneity in viral replication dynamics.
Bruurs LJM, Müller M, Schipper JG, Rabouw HH, Boersma S, van Kuppeveld FJM, Tanenbaum ME. Bruurs LJM, et al. Among authors: van kuppeveld fjm. Nat Microbiol. 2023 Nov;8(11):2115-2129. doi: 10.1038/s41564-023-01501-z. Epub 2023 Oct 9. Nat Microbiol. 2023. PMID: 37814072 Free PMC article.
260 results