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Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A.
Gonzalez-Menendez P, Phadke I, Olive ME, Joly A, Papoin J, Yan H, Galtier J, Platon J, Kang SWS, McGraw KL, Daumur M, Pouzolles M, Kondo T, Boireau S, Paul F, Young DJ, Lamure S, Mirmira RG, Narla A, Cartron G, Dunbar CE, Boyer-Clavel M, Porat-Shliom N, Dardalhon V, Zimmermann VS, Sitbon M, Dever TE, Mohandas N, Da Costa L, Udeshi ND, Blanc L, Kinet S, Taylor N. Gonzalez-Menendez P, et al. Blood. 2023 May 18;141(20):2520-2536. doi: 10.1182/blood.2022017584. Blood. 2023. PMID: 36735910
A boy with a novel homozygous ZAP70 mutation presenting with a dermatological phenotype and postnatal decrease in CD8+ T cells.
Babayeva R, Mongellaz C, Karakus IS, Cansever M, Bilgic Eltan S, Catak MC, Bulutoglu A, Kendir Demirkol Y, Eser M, Karakoc-Aydiner E, Ozen A, Zimmermann VS, Taylor N, Baris S. Babayeva R, et al. Pediatr Allergy Immunol. 2022 Mar;33(3):e13756. doi: 10.1111/pai.13756. Pediatr Allergy Immunol. 2022. PMID: 35338726 Free PMC article. No abstract available.
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, Daumur M, Dumé AS, Phadke I, Mongellaz C, Qu X, Bories PN, Fontenay M, An X, Dardalhon V, Sitbon M, Zimmermann VS, Gallagher PG, Tardito S, Blanc L, Mohandas N, Taylor N, Kinet S. Gonzalez-Menendez P, et al. Cell Rep. 2021 Feb 2;34(5):108723. doi: 10.1016/j.celrep.2021.108723. Cell Rep. 2021. PMID: 33535038 Free PMC article.
Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.
Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS. Pouzolles M, et al. J Allergy Clin Immunol. 2020 Feb;145(2):679-697.e5. doi: 10.1016/j.jaci.2019.08.029. Epub 2019 Sep 9. J Allergy Clin Immunol. 2020. PMID: 31513879 Free PMC article.