A boy with a novel homozygous ZAP70 mutation presenting with a dermatological phenotype and postnatal decrease in CD8+ T cells

A boy with a novel homozygous ZAP70 mutation presenting with a dermatological phenotype and postnatal decrease in CD8⁺ T cells

Pediatr Allergy Immunol. 2022 Mar;33(3):e13756. doi: 10.1111/pai.13756.

Royala Babayeva^{1

2

3}, Cedric Mongellaz⁴, Ibrahim Serhat Karakus⁵, Murat Cansever⁶, Sevgi Bilgic Eltan^{1

2

3}, Mehmet Cihangir Catak^{1

2

3}, Alper Bulutoglu^{1

2

3}, Yasemin Kendir Demirkol⁷, Metin Eser⁷, Elif Karakoc-Aydiner^{1

2

3}, Ahmet Ozen^{1

2

3}, Valérie S Zimmermann⁴, Naomi Taylor^{4

8}, Safa Baris^{1

2

3}

¹ Division of Pediatric Allergy and Immunology, School of Medicine, Marmara University, Istanbul, Turkey.
² Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey.
³ The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.
⁴ Institut de Genetique Moleculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.
⁵ School of Medicine, Marmara University, Istanbul, Turkey.
⁶ Ministry of Health, Pediatric Allergy and Immunology, Kayseri City Hospital, Kayseri, Turkey.
⁷ Division of Pediatric Genetics, Umraniye Education and Research Hospital, University of Health Sciences, Istanbul, Turkey.
⁸ Pediatric Oncology Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA.

No abstract available

Keywords: ZAP70; dermatitis; inborn errors of immunity; transplantation.