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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Among authors: wu j. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
Regenerative medicine: targeted genome editing in vivo.
Wang L, Wu J, Fang W, Liu GH, Izpisua Belmonte JC. Wang L, et al. Among authors: wu j. Cell Res. 2015 Mar;25(3):271-2. doi: 10.1038/cr.2015.11. Epub 2015 Jan 30. Cell Res. 2015. PMID: 25633595 Free PMC article.
CRISPR/Cas9 and TALE: beyond cut and paste.
Deng L, Ren R, Wu J, Suzuki K, Izpisua Belmote JC, Liu GH. Deng L, et al. Among authors: wu j. Protein Cell. 2015 Mar;6(3):157-159. doi: 10.1007/s13238-015-0137-5. Protein Cell. 2015. PMID: 25722052 Free PMC article.
Selective elimination of mitochondrial mutations in the germline by genome editing.
Reddy P, Ocampo A, Suzuki K, Luo J, Bacman SR, Williams SL, Sugawara A, Okamura D, Tsunekawa Y, Wu J, Lam D, Xiong X, Montserrat N, Esteban CR, Liu GH, Sancho-Martinez I, Manau D, Civico S, Cardellach F, Del Mar O'Callaghan M, Campistol J, Zhao H, Campistol JM, Moraes CT, Izpisua Belmonte JC. Reddy P, et al. Among authors: wu j. Cell. 2015 Apr 23;161(3):459-469. doi: 10.1016/j.cell.2015.03.051. Cell. 2015. PMID: 25910206 Free PMC article.
An alternative pluripotent state confers interspecies chimaeric competency.
Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, He Y, Li Z, Benner C, Tamura I, Krause MN, Nery JR, Du T, Zhang Z, Hishida T, Takahashi Y, Aizawa E, Kim NY, Lajara J, Guillen P, Campistol JM, Esteban CR, Ross PJ, Saghatelian A, Ren B, Ecker JR, Izpisua Belmonte JC. Wu J, et al. Nature. 2015 May 21;521(7552):316-21. doi: 10.1038/nature14413. Epub 2015 May 6. Nature. 2015. PMID: 25945737 Free PMC article.
Metabolic rescue in pluripotent cells from patients with mtDNA disease.
Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez NM, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, Wolf DP, Huang T, Terzic A, Laurent LC, Izpisua Belmonte JC, Mitalipov S. Ma H, et al. Among authors: wu j. Nature. 2015 Aug 13;524(7564):234-8. doi: 10.1038/nature14546. Epub 2015 Jul 15. Nature. 2015. PMID: 26176921
Metabolic exit from naive pluripotency.
Wu J, Izpisua Belmonte JC. Wu J, et al. Nat Cell Biol. 2015 Dec;17(12):1519-21. doi: 10.1038/ncb3269. Nat Cell Biol. 2015. PMID: 26612574
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