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Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection.
Burman N, Belukhina S, Depardieu F, Wilkinson RA, Skutel M, Santiago-Frangos A, Graham AB, Livenskyi A, Chechenina A, Morozova N, Zahl T, Henriques WS, Buyukyoruk M, Rouillon C, Shyrokova L, Kurata T, Hauryliuk V, Severinov K, Groseille J, Thierry A, Koszul R, Tesson F, Bernheim A, Bikard D, Wiedenheft B, Isaev A. Burman N, et al. Among authors: wilkinson ra. bioRxiv [Preprint]. 2024 Jan 9:2024.01.02.573894. doi: 10.1101/2024.01.02.573894. bioRxiv. 2024. PMID: 38260645 Free PMC article. Preprint.
Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays.
Santiago-Frangos A, Henriques WS, Wiegand T, Gauvin CC, Buyukyoruk M, Graham AB, Wilkinson RA, Triem L, Neselu K, Eng ET, Lander GC, Wiedenheft B. Santiago-Frangos A, et al. Among authors: wilkinson ra. Nat Struct Mol Biol. 2023 Nov;30(11):1675-1685. doi: 10.1038/s41594-023-01097-2. Epub 2023 Sep 14. Nat Struct Mol Biol. 2023. PMID: 37710013
Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic.
Nemudraia A, Nemudryi A, Buyukyoruk M, Scherffius AM, Zahl T, Wiegand T, Pandey S, Nichols JE, Hall LN, McVey A, Lee HH, Wilkinson RA, Snyder LR, Jones JD, Koutmou KS, Santiago-Frangos A, Wiedenheft B. Nemudraia A, et al. Among authors: wilkinson ra. Nat Commun. 2022 Dec 15;13(1):7762. doi: 10.1038/s41467-022-35445-5. Nat Commun. 2022. PMID: 36522348 Free PMC article.
Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic.
Nemudraia A, Nemudryi A, Buyukyoruk M, Scherffius AM, Zahl T, Wiegand T, Pandey S, Nichols JE, Hall L, McVey A, Lee HH, Wilkinson RA, Snyder LR, Jones JD, Koutmou KS, Santiago-Frangos A, Wiedenheft B. Nemudraia A, et al. Among authors: wilkinson ra. Res Sq [Preprint]. 2022 Apr 19:rs.3.rs-1466718. doi: 10.21203/rs.3.rs-1466718/v1. Res Sq. 2022. PMID: 35475170 Free PMC article. Updated. Preprint.
Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic.
Santiago-Frangos A, Hall LN, Nemudraia A, Nemudryi A, Krishna P, Wiegand T, Wilkinson RA, Snyder DT, Hedges JF, Cicha C, Lee HH, Graham A, Jutila MA, Taylor MP, Wiedenheft B. Santiago-Frangos A, et al. Among authors: wilkinson ra. Cell Rep Med. 2021 Jun 15;2(6):100319. doi: 10.1016/j.xcrm.2021.100319. Epub 2021 May 27. Cell Rep Med. 2021. PMID: 34075364 Free PMC article.
A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium.
Sebrell TA, Hashimi M, Sidar B, Wilkinson RA, Kirpotina L, Quinn MT, Malkoç Z, Taylor PJ, Wilking JN, Bimczok D. Sebrell TA, et al. Among authors: wilkinson ra. Cell Mol Gastroenterol Hepatol. 2019;8(1):157-171.e3. doi: 10.1016/j.jcmgh.2019.02.010. Epub 2019 Mar 13. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30878664 Free PMC article.
CRISPR RNA-guided autonomous delivery of Cas9.
Wilkinson RA, Martin C, Nemudryi AA, Wiedenheft B. Wilkinson RA, et al. Nat Struct Mol Biol. 2019 Jan;26(1):14-24. doi: 10.1038/s41594-018-0173-y. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598555 Free PMC article. Review.
81 results