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Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic.
Nemudraia A, Nemudryi A, Buyukyoruk M, Scherffius AM, Zahl T, Wiegand T, Pandey S, Nichols JE, Hall L, McVey A, Lee HH, Wilkinson RA, Snyder LR, Jones JD, Koutmou KS, Santiago-Frangos A, Wiedenheft B. Nemudraia A, et al. Among authors: wiedenheft b. Res Sq [Preprint]. 2022 Apr 19:rs.3.rs-1466718. doi: 10.21203/rs.3.rs-1466718/v1. Res Sq. 2022. PMID: 35475170 Free PMC article. Updated. Preprint.
A CRISPR method for genome engineering.
Wilkinson R, Wiedenheft B. Wilkinson R, et al. Among authors: wiedenheft b. F1000Prime Rep. 2014 Jan 2;6:3. doi: 10.12703/P6-3. eCollection 2014. F1000Prime Rep. 2014. PMID: 24592315 Free PMC article. Review.
The history and market impact of CRISPR RNA-guided nucleases.
van Erp PB, Bloomer G, Wilkinson R, Wiedenheft B. van Erp PB, et al. Among authors: wiedenheft b. Curr Opin Virol. 2015 Jun;12:85-90. doi: 10.1016/j.coviro.2015.03.011. Epub 2015 Apr 26. Curr Opin Virol. 2015. PMID: 25914022 Free PMC article.
Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System.
Qazi S, Miettinen HM, Wilkinson RA, McCoy K, Douglas T, Wiedenheft B. Qazi S, et al. Among authors: wiedenheft b. Mol Pharm. 2016 Mar 7;13(3):1191-6. doi: 10.1021/acs.molpharmaceut.5b00822. Epub 2016 Feb 22. Mol Pharm. 2016. PMID: 26894836 Free PMC article.
Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.
Rollins MF, Chowdhury S, Carter J, Golden SM, Wilkinson RA, Bondy-Denomy J, Lander GC, Wiedenheft B. Rollins MF, et al. Among authors: wiedenheft b. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5113-E5121. doi: 10.1073/pnas.1616395114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28438998 Free PMC article.
A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells.
Fang F, Angulo B, Xia N, Sukhwani M, Wang Z, Carey CC, Mazurie A, Cui J, Wilkinson R, Wiedenheft B, Irie N, Surani MA, Orwig KE, Reijo Pera RA. Fang F, et al. Among authors: wiedenheft b. Nat Cell Biol. 2018 Jun;20(6):655-665. doi: 10.1038/s41556-018-0094-3. Epub 2018 Apr 30. Nat Cell Biol. 2018. PMID: 29713018 Free PMC article.
CRISPR RNA-guided autonomous delivery of Cas9.
Wilkinson RA, Martin C, Nemudryi AA, Wiedenheft B. Wilkinson RA, et al. Among authors: wiedenheft b. Nat Struct Mol Biol. 2019 Jan;26(1):14-24. doi: 10.1038/s41594-018-0173-y. Epub 2018 Dec 31. Nat Struct Mol Biol. 2019. PMID: 30598555 Free PMC article. Review.
Cas9 slide-and-seek for phage defense and genome engineering.
Santiago-Frangos A, Wiegand T, Wiedenheft B. Santiago-Frangos A, et al. Among authors: wiedenheft b. EMBO J. 2019 Feb 15;38(4):e101474. doi: 10.15252/embj.2019101474. Epub 2019 Feb 7. EMBO J. 2019. PMID: 30733242 Free PMC article.
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