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Fragment-to-Lead Medicinal Chemistry Publications in 2020.
de Esch IJP, Erlanson DA, Jahnke W, Johnson CN, Walsh L. de Esch IJP, et al. Among authors: walsh l. J Med Chem. 2022 Jan 13;65(1):84-99. doi: 10.1021/acs.jmedchem.1c01803. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928151 Free PMC article. Review.
A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT).
Lanier M, Ambrus G, Cole DC, Davenport R, Ellery J, Fosbeary R, Jennings AJ, Kadotani A, Kamada Y, Kamran R, Matsumoto S, Mizukami A, Okubo S, Okada K, Saikatendu K, Walsh L, Wu H, Hixon MS. Lanier M, et al. Among authors: walsh l. J Med Chem. 2014 Jun 26;57(12):5459-63. doi: 10.1021/jm500475k. Epub 2014 Jun 4. J Med Chem. 2014. PMID: 24847974
Fragment-to-Lead Medicinal Chemistry Publications in 2021.
Walsh L, Erlanson DA, de Esch IJP, Jahnke W, Woodhead A, Wren E. Walsh L, et al. J Med Chem. 2023 Jan 26;66(2):1137-1156. doi: 10.1021/acs.jmedchem.2c01827. Epub 2023 Jan 9. J Med Chem. 2023. PMID: 36622056 Review.
Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.
Howley E, Bestwick M, Fradley R, Harrison H, Leveridge M, Okada K, Fieldhouse C, Farnaby W, Canning H, Sykes AP, Merchant K, Hazel K, Kerr C, Kinsella N, Walsh L, Livermore DG, Hoffman I, Ellery J, Mitchell P, Patel T, Carlton M, Barnes M, Miller DJ. Howley E, et al. Among authors: walsh l. Neurochem Res. 2017 Nov;42(11):3279-3288. doi: 10.1007/s11064-017-2367-9. Epub 2017 Aug 5. Neurochem Res. 2017. PMID: 28780732
Application of Nanomaterials in Endodontics.
Afkhami F, Chen Y, Walsh LJ, Peters OA, Xu C. Afkhami F, et al. Among authors: walsh lj. BME Front. 2024 Apr 17;5:0043. doi: 10.34133/bmef.0043. eCollection 2024. BME Front. 2024. PMID: 38711803 Free PMC article. Review.
1,162 results