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Page 1
Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis.
Hutter S, van Haaften WT, Hünerwadel A, Baebler K, Herfarth N, Raselli T, Mamie C, Misselwitz B, Rogler G, Weder B, Dijkstra G, Meier CF, de Vallière C, Weber A, Imenez Silva PH, Wagner CA, Frey-Wagner I, Ruiz PA, Hausmann M. Hutter S, et al. Among authors: wagner ca. J Crohns Colitis. 2018 Nov 15;12(11):1348-1358. doi: 10.1093/ecco-jcc/jjy118. J Crohns Colitis. 2018. PMID: 30165600
G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G. de Vallière C, et al. Among authors: wagner ca. Inflamm Bowel Dis. 2015 Jun;21(6):1269-81. doi: 10.1097/MIB.0000000000000375. Inflamm Bowel Dis. 2015. PMID: 25856770 Free PMC article.
The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment.
de Vallière C, Vidal S, Clay I, Jurisic G, Tcymbarevich I, Lang S, Ludwig MG, Okoniewski M, Eloranta JJ, Kullak-Ublick GA, Wagner CA, Rogler G, Seuwen K. de Vallière C, et al. Among authors: wagner ca. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G475-90. doi: 10.1152/ajpgi.00408.2014. Epub 2015 Jul 23. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 26206859 Free article.
And the fat lady sings about phosphate and calcium.
Wagner CA, Imenez Silva PH, Rubio-Aliaga I. Wagner CA, et al. Kidney Int. 2017 Feb;91(2):270-272. doi: 10.1016/j.kint.2016.11.009. Kidney Int. 2017. PMID: 28087005 Free article.
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA. de Vallière C, et al. Among authors: wagner ca. Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov. Cell Mol Gastroenterol Hepatol. 2016. PMID: 28174749 Free PMC article.
The Proton-activated Receptor GPR4 Modulates Intestinal Inflammation.
Wang Y, de Vallière C, Imenez Silva PH, Leonardi I, Gruber S, Gerstgrasser A, Melhem H, Weber A, Leucht K, Wolfram L, Hausmann M, Krieg C, Thomasson K, Boyman O, Frey-Wagner I, Rogler G, Wagner CA. Wang Y, et al. Among authors: wagner ca. J Crohns Colitis. 2018 Feb 28;12(3):355-368. doi: 10.1093/ecco-jcc/jjx147. J Crohns Colitis. 2018. PMID: 29136128 Free article.
Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men.
Daryadel A, Bettoni C, Haider T, Imenez Silva PH, Schnitzbauer U, Pastor-Arroyo EM, Wenger RH, Gassmann M, Wagner CA. Daryadel A, et al. Among authors: wagner ca. Pflugers Arch. 2018 Oct;470(10):1569-1582. doi: 10.1007/s00424-018-2171-7. Epub 2018 Jul 2. Pflugers Arch. 2018. PMID: 29961920 Free article. Clinical Trial.
Lack of the pH-sensing Receptor TDAG8 [GPR65] in Macrophages Plays a Detrimental Role in Murine Models of Inflammatory Bowel Disease.
Tcymbarevich I, Richards SM, Russo G, Kühn-Georgijevic J, Cosin-Roger J, Baebler K, Lang S, Bengs S, Atrott K, Bettoni C, Gruber S, Frey-Wagner I, Scharl M, Misselwitz B, Wagner CA, Seuwen K, Rogler G, Ruiz PA, Spalinger M, de Vallière C. Tcymbarevich I, et al. Among authors: wagner ca. J Crohns Colitis. 2019 Feb 1;13(2):245-258. doi: 10.1093/ecco-jcc/jjy152. J Crohns Colitis. 2019. PMID: 30535144
The impact of the rs8005161 polymorphism on G protein-coupled receptor GPR65 (TDAG8) pH-associated activation in intestinal inflammation.
Tcymbarevich IV, Eloranta JJ, Rossel JB, Obialo N, Spalinger M, Cosin-Roger J, Lang S, Kullak-Ublick GA, Wagner CA, Scharl M, Seuwen K, Ruiz PA, Rogler G, de Vallière C, Misselwitz B; Swiss IBD Cohort Study Group. Tcymbarevich IV, et al. Among authors: wagner ca. BMC Gastroenterol. 2019 Jan 7;19(1):2. doi: 10.1186/s12876-018-0922-8. BMC Gastroenterol. 2019. PMID: 30616622 Free PMC article.
376 results