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Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+ T cells.
Winkler F, Hipp AV, Ramirez C, Martin B, Villa M, Neuwirt E, Gorka O, Aerssens J, Johansson SE, Rana N, Llewellyn-Lacey S, Price DA, Panning M, Groß O, Pearce EL, Hermann CM, Schumann K, Hannibal L, Neumann-Haefelin C, Boettler T, Knolle P, Hofmann M, Wohlleber D, Thimme R, Bengsch B. Winkler F, et al. Among authors: villa m. Gut. 2023 Oct;72(10):1971-1984. doi: 10.1136/gutjnl-2022-328734. Epub 2023 Aug 4. Gut. 2023. PMID: 37541771 Free PMC article.
Ancillary Activity: Beyond Core Metabolism in Immune Cells.
Puleston DJ, Villa M, Pearce EL. Puleston DJ, et al. Among authors: villa m. Cell Metab. 2017 Jul 5;26(1):131-141. doi: 10.1016/j.cmet.2017.06.019. Cell Metab. 2017. PMID: 28683280 Free PMC article. Review.
A Sweet Deal for Diabetes.
Villa M, Qiu J, Pearce EL. Villa M, et al. Trends Endocrinol Metab. 2018 Jan;29(1):1-2. doi: 10.1016/j.tem.2017.10.006. Trends Endocrinol Metab. 2018. PMID: 29102469
Potassium shapes antitumor immunity.
Baixauli F, Villa M, Pearce EL. Baixauli F, et al. Among authors: villa m. Science. 2019 Mar 29;363(6434):1395-1396. doi: 10.1126/science.aaw8800. Science. 2019. PMID: 30923211 No abstract available.
Acetate Promotes T Cell Effector Function during Glucose Restriction.
Qiu J, Villa M, Sanin DE, Buck MD, O'Sullivan D, Ching R, Matsushita M, Grzes KM, Winkler F, Chang CH, Curtis JD, Kyle RL, Van Teijlingen Bakker N, Corrado M, Haessler F, Alfei F, Edwards-Hicks J, Maggi LB Jr, Zehn D, Egawa T, Bengsch B, Klein Geltink RI, Jenuwein T, Pearce EJ, Pearce EL. Qiu J, et al. Among authors: villa m. Cell Rep. 2019 May 14;27(7):2063-2074.e5. doi: 10.1016/j.celrep.2019.04.022. Cell Rep. 2019. PMID: 31091446 Free PMC article.
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity.
Corrado M, Edwards-Hicks J, Villa M, Flachsmann LJ, Sanin DE, Jacobs M, Baixauli F, Stanczak M, Anderson E, Azuma M, Quintana A, Curtis JD, Clapes T, Grzes KM, Kabat AM, Kyle R, Patterson AE, Geltink RK, Amulic B, Steward CG, Strathdee D, Trompouki E, O'Sullivan D, Pearce EJ, Pearce EL. Corrado M, et al. Among authors: villa m. Cell Metab. 2020 Dec 1;32(6):981-995.e7. doi: 10.1016/j.cmet.2020.11.003. Cell Metab. 2020. PMID: 33264603 Free PMC article.
Glucose makes Treg lose their temper.
Villa M, O'Sullivan D, Pearce EL. Villa M, et al. Cancer Cell. 2021 Apr 12;39(4):460-462. doi: 10.1016/j.ccell.2021.03.001. Cancer Cell. 2021. PMID: 33848476 Free article.
Fever supports CD8+ effector T cell responses by promoting mitochondrial translation.
O'Sullivan D, Stanczak MA, Villa M, Uhl FM, Corrado M, Klein Geltink RI, Sanin DE, Apostolova P, Rana N, Edwards-Hicks J, Grzes KM, Kabat AM, Kyle RL, Fabri M, Curtis JD, Buck MD, Patterson AE, Regina A, Field CS, Baixauli F, Puleston DJ, Pearce EJ, Zeiser R, Pearce EL. O'Sullivan D, et al. Among authors: villa m. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2023752118. doi: 10.1073/pnas.2023752118. Epub 2021 Jun 14. Proc Natl Acad Sci U S A. 2021. PMID: 34161266 Free PMC article.
Plasmacytoid dendritic cell activation is dependent on coordinated expression of distinct amino acid transporters.
Grzes KM, Sanin DE, Kabat AM, Stanczak MA, Edwards-Hicks J, Matsushita M, Hackl A, Hässler F, Knoke K, Zahalka S, Villa M, Kofler DM, Voll RE, Zigrino P, Fabri M, Pearce EL, Pearce EJ. Grzes KM, et al. Among authors: villa m. Immunity. 2021 Nov 9;54(11):2514-2530.e7. doi: 10.1016/j.immuni.2021.10.009. Epub 2021 Oct 29. Immunity. 2021. PMID: 34717796 Free article.
1,362 results