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Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NY, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J. Lalaoui N, et al. Among authors: vaux dl. Cancer Cell. 2016 Feb 8;29(2):145-58. doi: 10.1016/j.ccell.2016.01.006. Cancer Cell. 2016. PMID: 26859455 Free article.
HtrA2/Omi, a sheep in wolf's clothing.
Vaux DL, Silke J. Vaux DL, et al. Cell. 2003 Oct 31;115(3):251-3. doi: 10.1016/s0092-8674(03)00851-1. Cell. 2003. PMID: 14636553 Free article.
The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.
Brumatti G, Ma C, Lalaoui N, Nguyen NY, Navarro M, Tanzer MC, Richmond J, Ghisi M, Salmon JM, Silke N, Pomilio G, Glaser SP, de Valle E, Gugasyan R, Gurthridge MA, Condon SM, Johnstone RW, Lock R, Salvesen G, Wei A, Vaux DL, Ekert PG, Silke J. Brumatti G, et al. Among authors: vaux dl. Sci Transl Med. 2016 May 18;8(339):339ra69. doi: 10.1126/scitranslmed.aad3099. Sci Transl Med. 2016. PMID: 27194727
Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Lalaoui N, Hänggi K, Brumatti G, Chau D, Nguyen NN, Vasilikos L, Spilgies LM, Heckmann DA, Ma C, Ghisi M, Salmon JM, Matthews GM, de Valle E, Moujalled DM, Menon MB, Spall SK, Glaser SP, Richmond J, Lock RB, Condon SM, Gugasyan R, Gaestel M, Guthridge M, Johnstone RW, Munoz L, Wei A, Ekert PG, Vaux DL, Wong WW, Silke J. Lalaoui N, et al. Among authors: vaux dl. Cancer Cell. 2016 Sep 12;30(3):499-500. doi: 10.1016/j.ccell.2016.08.009. Epub 2016 Sep 12. Cancer Cell. 2016. PMID: 27622337 Free article. No abstract available.
Mammalian mitochondrial IAP binding proteins.
Vaux DL, Silke J. Vaux DL, et al. Biochem Biophys Res Commun. 2003 May 9;304(3):499-504. doi: 10.1016/s0006-291x(03)00622-3. Biochem Biophys Res Commun. 2003. PMID: 12729584 Review.
IAPs, RINGs and ubiquitylation.
Vaux DL, Silke J. Vaux DL, et al. Nat Rev Mol Cell Biol. 2005 Apr;6(4):287-97. doi: 10.1038/nrm1621. Nat Rev Mol Cell Biol. 2005. PMID: 15803136 Review.
177 results