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Page 1
Bioaffinity Mass Spectrometry Screening.
Yang B, Feng YJ, Vu H, McCormick B, Rowley J, Pedro L, Crowther GJ, Van Voorhis WC, Forster PI, Quinn RJ. Yang B, et al. Among authors: van voorhis wc. J Biomol Screen. 2016 Feb;21(2):194-200. doi: 10.1177/1087057115622605. J Biomol Screen. 2016. PMID: 26773071
Buffer optimization of thermal melt assays of Plasmodium proteins for detection of small-molecule ligands.
Crowther GJ, Napuli AJ, Thomas AP, Chung DJ, Kovzun KV, Leibly DJ, Castaneda LJ, Bhandari J, Damman CJ, Hui R, Hol WG, Buckner FS, Verlinde CL, Zhang Z, Fan E, van Voorhis WC. Crowther GJ, et al. Among authors: van voorhis wc. J Biomol Screen. 2009 Jul;14(6):700-7. doi: 10.1177/1087057109335749. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470714 Free PMC article.
Use of thermal melt curves to assess the quality of enzyme preparations.
Crowther GJ, He P, Rodenbough PP, Thomas AP, Kovzun KV, Leibly DJ, Bhandari J, Castaneda LJ, Hol WG, Gelb MH, Napuli AJ, Van Voorhis WC. Crowther GJ, et al. Among authors: van voorhis wc. Anal Biochem. 2010 Apr 15;399(2):268-75. doi: 10.1016/j.ab.2009.12.018. Epub 2009 Dec 14. Anal Biochem. 2010. PMID: 20018159 Free PMC article.
Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.
Crowther GJ, Napuli AJ, Gilligan JH, Gagaring K, Borboa R, Francek C, Chen Z, Dagostino EF, Stockmyer JB, Wang Y, Rodenbough PP, Castaneda LJ, Leibly DJ, Bhandari J, Gelb MH, Brinker A, Engels IH, Taylor J, Chatterjee AK, Fantauzzi P, Glynne RJ, Van Voorhis WC, Kuhen KL. Crowther GJ, et al. Among authors: van voorhis wc. Mol Biochem Parasitol. 2011 Jan;175(1):21-9. doi: 10.1016/j.molbiopara.2010.08.005. Epub 2010 Sep 15. Mol Biochem Parasitol. 2011. PMID: 20813141 Free PMC article.
Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline.
Hewitt SN, Choi R, Kelley A, Crowther GJ, Napuli AJ, Van Voorhis WC. Hewitt SN, et al. Among authors: van voorhis wc. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1006-9. doi: 10.1107/S1744309111022159. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904041 Free PMC article.
Cofactor-independent phosphoglycerate mutase from nematodes has limited druggability, as revealed by two high-throughput screens.
Crowther GJ, Booker ML, He M, Li T, Raverdy S, Novelli JF, He P, Dale NR, Fife AM, Barker RH Jr, Kramer ML, Van Voorhis WC, Carlow CK, Wang MW. Crowther GJ, et al. Among authors: van voorhis wc. PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2628. doi: 10.1371/journal.pntd.0002628. eCollection 2014. PLoS Negl Trop Dis. 2014. PMID: 24416464 Free PMC article.
The Bacterial Sec Pathway of Protein Export: Screening and Follow-Up.
Crowther GJ, Weller SM, Jones JC, Weaver T, Fan E, Van Voorhis WC, Rosen H. Crowther GJ, et al. Among authors: van voorhis wc. J Biomol Screen. 2015 Aug;20(7):921-6. doi: 10.1177/1087057115587458. Epub 2015 May 18. J Biomol Screen. 2015. PMID: 25987586
327 results