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Chronic pain causes Tau-mediated hippocampal pathology and memory deficits.
Guerreiro SR, Guimarães MR, Silva JM, Dioli C, Vamvaka-Iakovou A, Sousa R, Gomes P, Megalokonomou A, Campos-Marques C, Cunha AM, Almeida A, Sousa N, Leite-Almeida H, Sotiropoulos I. Guerreiro SR, et al. Among authors: vamvaka iakovou a. Mol Psychiatry. 2022 Nov;27(11):4385-4393. doi: 10.1038/s41380-022-01707-3. Epub 2022 Sep 2. Mol Psychiatry. 2022. PMID: 36056171
Extracellular vesicles and Alzheimer's disease in the novel era of Precision Medicine: implications for disease progression, diagnosis and treatment.
Gomes P, Tzouanou F, Skolariki K, Vamvaka-Iakovou A, Noguera-Ortiz C, Tsirtsaki K, Waites CL, Vlamos P, Sousa N, Costa-Silva B, Kapogiannis D, Sotiropoulos I. Gomes P, et al. Among authors: vamvaka iakovou a. Exp Neurol. 2022 Dec;358:114183. doi: 10.1016/j.expneurol.2022.114183. Epub 2022 Aug 8. Exp Neurol. 2022. PMID: 35952764 Free PMC article. Review.
Chronic pain inhibits autophagy in hippocampus while the analgetic drug, Gabapentin reverts this SNI-driven action.
Guerreiro SR, Guimarães MR, Silva JM, Dioli C, Vamvaka-Iakovou A, Sousa R, Gomes P, Megalokonomou A, Campos-Marques C, Cunha AM, Almeida A, Sousa N, Leite-Almeida H, Sotiropoulos I. Guerreiro SR, et al. Among authors: vamvaka iakovou a. Mol Psychiatry. 2022 Nov;27(11):4371. doi: 10.1038/s41380-022-01874-3. Mol Psychiatry. 2022. PMID: 36494573 No abstract available.