1 Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.
2 ICVS/3B's - PT Government Associate Laboratory, Braga, Guimarães, Portugal.
3 Institute of Biosciences and Applications, NCSR Demokritos, Athens, Greece.
4 Medical School, University of Crete, Heraklion, Greece.
5 Clinical Academic Center (2CA), Braga, Portugal.
6 Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal. hugoalmeida@med.uminho.pt.
8 Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal. ioannis@med.uminho.pt.