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Molecular docking and dynamic studies of a potential therapeutic target inhibiting glyoxalase system: Metabolic action of the 3, 3 '- [3- (5-chloro-2-hydroxyphenyl) -3-oxopropane-1, 1-diyl] - Bis-4-hydroxycoumarin leads overexpression of the intracellular level of methylglyoxal and induction of a pro-apoptotic phenomenon in a hepatocellular carcinoma model.
Taïbi N, Al-Balas QA, Bekari N, Talhi O, Al Jabal GA, Benali Y, Ameraoui R, Hadjadj M, Taïbi A, Boutaiba ZM, Abou-Mustapha M, Khammar F, Dergal F, Hassaine R, Boukenna L, Bachari K, Soares Silva AM. Taïbi N, et al. Among authors: talhi o. Chem Biol Interact. 2021 Aug 25;345:109511. doi: 10.1016/j.cbi.2021.109511. Epub 2021 May 11. Chem Biol Interact. 2021. PMID: 33989593
Advances in Spirocyclic Hybrids: Chemistry and Medicinal Actions.
Benabdallah M, Talhi O, Nouali F, Choukchou-Braham N, Bachari K, Silva AMS. Benabdallah M, et al. Among authors: talhi o. Curr Med Chem. 2018;25(31):3748-3767. doi: 10.2174/0929867325666180309124821. Curr Med Chem. 2018. PMID: 29521213 Review.
Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release.
Mazumder A, Lee JY, Talhi O, Cerella C, Chateauvieux S, Gaigneaux A, Hong CR, Kang HJ, Lee Y, Kim KW, Kim DW, Shin HY, Dicato M, Bachari K, Silva AMS, Orlikova-Boyer B, Diederich M. Mazumder A, et al. Among authors: talhi o. Cancer Lett. 2018 Dec 1;438:197-218. doi: 10.1016/j.canlet.2018.07.041. Epub 2018 Sep 8. Cancer Lett. 2018. PMID: 30205168
14 results