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Discovery of a Novel Non-Narcotic Analgesic Derived from the CL-20 Explosive: Synthesis, Pharmacology, and Target Identification of Thiowurtzine, a Potent Inhibitor of the Opioid Receptors and the Ion Channels.
Aguero S, Megy S, Eremina VV, Kalashnikov AI, Krylova SG, Kulagina DA, Lopatina KA, Fournier M, Povetyeva TN, Vorozhtsov AB, Sysolyatin SV, Zhdanov VV, Terreux R. Aguero S, et al. Among authors: sysolyatin sv. ACS Omega. 2021 May 31;6(23):15400-15411. doi: 10.1021/acsomega.1c01786. eCollection 2021 Jun 15. ACS Omega. 2021. PMID: 34151118 Free PMC article.
Analgesic Activity of Hexaazaisowurtzitane Derivatives.
Krylova SG, Povet'eva TN, Zueva EP, Suslov NI, Amosova EN, Razina TG, Lopatina KA, Rybalkina OY, Nesterova YV, Afanas'eva OG, Kiseleva EA, Sysolyatin SV, Kulagina DA, Zhdanov VV. Krylova SG, et al. Among authors: sysolyatin sv. Bull Exp Biol Med. 2019 Feb;166(4):461-465. doi: 10.1007/s10517-019-04372-9. Epub 2019 Feb 20. Bull Exp Biol Med. 2019. PMID: 30788739
Pharmacokinetics of a New Analgesic on the Basis of Hexaazaisowurtzitane Derivative.
Bryushinina OS, Yanovskaya EA, Abdrashitova NY, Zyuz'kova YG, Frelikh GA, Lopatina KA, Zueva EP, Krylova SG, Kulagina DA, Sysolyatin SV, Udut VV. Bryushinina OS, et al. Among authors: sysolyatin sv. Bull Exp Biol Med. 2021 Feb;170(4):448-452. doi: 10.1007/s10517-021-05085-8. Epub 2021 Mar 13. Bull Exp Biol Med. 2021. PMID: 33713224
Some Aspects of Investigation of the Central Mechanism of Antinociceptive Effect of a New Analgetic from the Hexaazaisowurtzitane Group.
Krylova SG, Lopatina KA, Nesterova YV, Povet'eva TN, Kul'pin PV, Afanas'eva OG, Kulagina DA, Safonova EA, Zueva EP, Suslov NI, Sysolyatin SV. Krylova SG, et al. Among authors: sysolyatin sv. Bull Exp Biol Med. 2021 Apr;170(6):752-758. doi: 10.1007/s10517-021-05148-w. Epub 2021 Apr 24. Bull Exp Biol Med. 2021. PMID: 33893965
Promising New Salt of Oseltamivir.
Kalashnikov AI, Sonina EG, Kulagina DA, Sysolyatin SV, Prokop'eva EA, Sherstoboev EY. Kalashnikov AI, et al. Among authors: sysolyatin sv. Pharm Chem J. 2021;55(6):540-543. doi: 10.1007/s11094-021-02456-3. Epub 2021 Sep 25. Pharm Chem J. 2021. PMID: 34602660 Free PMC article.
Antinociceptive Effect of Ethowurtzine, a New Compound from the Class of Hexaazaizowurzitane.
Krylova SG, Kiseleva EA, Povet'eva TN, Nesterova YV, Rybalkina OY, Kul'pin PV, Afanas'eva OG, Kulagina DA, Eremina VV, Baibakova OV, Zueva EP, Suslov NI, Sysolyatin SV, Zhdanov VV. Krylova SG, et al. Among authors: sysolyatin sv. Bull Exp Biol Med. 2022 Dec;174(2):230-235. doi: 10.1007/s10517-023-05679-4. Epub 2023 Jan 4. Bull Exp Biol Med. 2022. PMID: 36598664
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