Svobodova L - Search Results

1

Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimeŕs drugs dealing with cholinergic, amyloid and mitochondrial systems.

Nepovimova E, Svobodova L, Dolezal R, Hepnarova V, Junova L, Jun D, Korabecny J, Kucera T, Gazova Z, Motykova K, Kubackova J, Bednarikova Z, Janockova J, Jesus C, Cortes L, Pina J, Rostohar D, Serpa C, Soukup O, Aitken L, Hughes RE, Musilek K, Muckova L, Jost P, Chvojkova M, Vales K, Valis M, Chrienova Z, Chalupova K, Kuca K. Nepovimova E, et al. Among authors: svobodova l. Bioorg Chem. 2021 Feb;107:104596. doi: 10.1016/j.bioorg.2020.104596. Epub 2020 Dec 28. Bioorg Chem. 2021. PMID: 33421953

2

Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II-Design, Synthesis, and Evaluation.

Maryška M, Svobodová L, Dehaen W, Hrabinová M, Rumlová M, Soukup O, Kuchař M. Maryška M, et al. Among authors: svobodova l. Pharmaceuticals (Basel). 2021 Dec 10;14(12):1291. doi: 10.3390/ph14121291. Pharmaceuticals (Basel). 2021. PMID: 34959692 Free PMC article.

3

Allosteric modulation of the nicotinic acetylcholine receptor by physostigmine.

Svobodová L, Krusek J, Hendrych T, Vyskocil F. Svobodová L, et al. Ann N Y Acad Sci. 2005 Jun;1048:355-8. doi: 10.1196/annals.1342.037. Ann N Y Acad Sci. 2005. PMID: 16154951

4

Targeted neural differentiation of murine mesenchymal stem cells by a protocol simulating the inflammatory site of neural injury.

Chudickova M, Bruza P, Zajicova A, Trosan P, Svobodova L, Javorkova E, Kubinova S, Holan V. Chudickova M, et al. Among authors: svobodova l. J Tissue Eng Regen Med. 2017 May;11(5):1588-1597. doi: 10.1002/term.2059. Epub 2015 Jun 29. J Tissue Eng Regen Med. 2017. PMID: 26118945

5

Physostigmine modulation of acetylcholine currents in COS cells transfected with mouse muscle nicotinic receptor.

Svobodová L, Krůsek J, Hendrych T, Vyskocil F. Svobodová L, et al. Neurosci Lett. 2006 Jun 19;401(1-2):20-4. doi: 10.1016/j.neulet.2006.02.065. Epub 2006 Mar 13. Neurosci Lett. 2006. PMID: 16530961

6

Role of negatively charged amino acids in beta 4 F-loop in activation and desensitization of alpha 3 beta 4 rat neuronal nicotinic receptors.

Lindovský J, Kaniaková M, Svobodová L, Vyskocil F, Krůsek J. Lindovský J, et al. Among authors: svobodova l. Biochim Biophys Acta. 2008 Apr;1778(4):864-71. doi: 10.1016/j.bbamem.2008.01.010. Epub 2008 Jan 16. Biochim Biophys Acta. 2008. PMID: 18249185 Free article.

7

Activation and modulation of ligand-gated ion channels.

Krůsek J, Dittert I, Hendrych T, Hník P, Horák M, Petrovic M, Sedlácek M, Susánková K, Svobodová L, Tousová K, Ujec E, Vlachová V, Vyklický L, Vyskocil F, Vyklický L Jr. Krůsek J, et al. Among authors: svobodova l. Physiol Res. 2004;53 Suppl 1:S103-13. Physiol Res. 2004. PMID: 15119941 Free article. Review.

8

Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure.

Balsera B, Mulet J, Fernández-Carvajal A, de la Torre-Martínez R, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, Sala S, Sala F, Criado M. Balsera B, et al. Among authors: svobodova l. Eur J Med Chem. 2014 Oct 30;86:724-39. doi: 10.1016/j.ejmech.2014.09.039. Epub 2014 Sep 16. Eur J Med Chem. 2014. PMID: 25232969

9

Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in mice.

Dubisova J, Burianova JS, Svobodova L, Makovicky P, Martinez-Varea N, Cimpean A, Fawcett JW, Kwok JCF, Kubinova S. Dubisova J, et al. Among authors: svobodova l. Brain Res Bull. 2022 Apr;181:144-156. doi: 10.1016/j.brainresbull.2022.01.011. Epub 2022 Jan 21. Brain Res Bull. 2022. PMID: 35066096 Free PMC article.

10

The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism.

Aimová D, Svobodová L, Kotrbová V, Mrázová B, Hodek P, Hudecek J, Václavíková R, Frei E, Stiborová M. Aimová D, et al. Among authors: svobodova l. Drug Metab Dispos. 2007 Oct;35(10):1926-34. doi: 10.1124/dmd.107.016048. Epub 2007 Jul 26. Drug Metab Dispos. 2007. PMID: 17656468

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