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Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies.
Perrett HR, Brouwer PJM, Hurtado J, Newby ML, Liu L, Müller-Kräuter H, Müller Aguirre S, Burger JA, Bouhuijs JH, Gibson G, Messmer T, Schieffelin JS, Antanasijevic A, Boons GJ, Strecker T, Crispin M, Sanders RW, Briney B, Ward AB. Perrett HR, et al. Among authors: strecker t. Cell Rep. 2023 May 30;42(5):112524. doi: 10.1016/j.celrep.2023.112524. Epub 2023 May 18. Cell Rep. 2023. PMID: 37209096 Free PMC article.
Structure of the Lassa virus glycan shield provides a model for immunological resistance.
Watanabe Y, Raghwani J, Allen JD, Seabright GE, Li S, Moser F, Huiskonen JT, Strecker T, Bowden TA, Crispin M. Watanabe Y, et al. Among authors: strecker t. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7320-7325. doi: 10.1073/pnas.1803990115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941589 Free PMC article.
Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection.
Brouwer PJM, Antanasijevic A, Ronk AJ, Müller-Kräuter H, Watanabe Y, Claireaux M, Perrett HR, Bijl TPL, Grobben M, Umotoy JC, Schriek AI, Burger JA, Tejjani K, Lloyd NM, Steijaert TH, van Haaren MM, Sliepen K, de Taeye SW, van Gils MJ, Crispin M, Strecker T, Bukreyev A, Ward AB, Sanders RW. Brouwer PJM, et al. Among authors: strecker t. Cell Host Microbe. 2022 Dec 14;30(12):1759-1772.e12. doi: 10.1016/j.chom.2022.10.018. Epub 2022 Nov 17. Cell Host Microbe. 2022. PMID: 36400021 Free PMC article.
Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Brouwer PJM, Perrett HR, Beaumont T, Nijhuis H, Kruijer S, Burger JA, Lee WH, Müller-Kraüter H, Sanders RW, Strecker T, van Gils MJ, Ward AB. Brouwer PJM, et al. Among authors: strecker t. bioRxiv [Preprint]. 2023 Dec 23:2023.12.21.572918. doi: 10.1101/2023.12.21.572918. bioRxiv. 2023. PMID: 38187682 Free PMC article. Preprint.
Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity.
Müller H, Fehling SK, Dorna J, Urbanowicz RA, Oestereich L, Krebs Y, Kolesnikova L, Schauflinger M, Krähling V, Magassouba N, Fichet-Calvet E, Ball JK, Kaufmann A, Bauer S, Becker S, von Messling V, Strecker T. Müller H, et al. Among authors: strecker t. NPJ Vaccines. 2020 Aug 4;5(1):71. doi: 10.1038/s41541-020-00219-x. eCollection 2020. NPJ Vaccines. 2020. PMID: 32802410 Free PMC article.
183 results