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The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.
Stormo AED, Shavarebi F, FitzGibbon M, Earley EM, Ahrendt H, Lum LS, Verschueren E, Swaney DL, Skibinski G, Ravisankar A, van Haren J, Davis EJ, Johnson JR, Von Dollen J, Balen C, Porath J, Crosio C, Mirescu C, Iaccarino C, Dauer WT, Nichols RJ, Wittmann T, Cox TC, Finkbeiner S, Krogan NJ, Oakes SA, Hiniker A. Stormo AED, et al. Among authors: skibinski g. J Cell Biol. 2022 Apr 4;221(4):e202010065. doi: 10.1083/jcb.202010065. Epub 2022 Mar 10. J Cell Biol. 2022. PMID: 35266954 Free PMC article.
iPS cells in the study of PD molecular pathogenesis.
Cobb MM, Ravisankar A, Skibinski G, Finkbeiner S. Cobb MM, et al. Among authors: skibinski g. Cell Tissue Res. 2018 Jul;373(1):61-77. doi: 10.1007/s00441-017-2749-y. Epub 2017 Dec 12. Cell Tissue Res. 2018. PMID: 29234887 Free PMC article. Review.
In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images.
Christiansen EM, Yang SJ, Ando DM, Javaherian A, Skibinski G, Lipnick S, Mount E, O'Neil A, Shah K, Lee AK, Goyal P, Fedus W, Poplin R, Esteva A, Berndl M, Rubin LL, Nelson P, Finkbeiner S. Christiansen EM, et al. Among authors: skibinski g. Cell. 2018 Apr 19;173(3):792-803.e19. doi: 10.1016/j.cell.2018.03.040. Epub 2018 Apr 12. Cell. 2018. PMID: 29656897 Free PMC article.
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson's disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007).
Novak G, Finkbeiner S, Skibinski G, Skupin A. Novak G, et al. Among authors: skibinski g. Stem Cell Res. 2021 Dec;57:102600. doi: 10.1016/j.scr.2021.102600. Epub 2021 Nov 22. Stem Cell Res. 2021. PMID: 34826737 Free PMC article.
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. Nakamura K, et al. Among authors: skibinski g. J Biol Chem. 2011 Jun 10;286(23):20710-26. doi: 10.1074/jbc.M110.213538. Epub 2011 Apr 13. J Biol Chem. 2011. PMID: 21489994 Free PMC article.
95 results