Simmonds P - Search Results

1

Uncovering viral RNA-host cell interactions on a proteome-wide scale.

Iselin L, Palmalux N, Kamel W, Simmonds P, Mohammed S, Castello A. Iselin L, et al. Among authors: simmonds p. Trends Biochem Sci. 2022 Jan;47(1):23-38. doi: 10.1016/j.tibs.2021.08.002. Epub 2021 Sep 9. Trends Biochem Sci. 2022. PMID: 34509361 Free PMC article. Review.

2

Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA.

Simmonds P, Ansari MA. Simmonds P, et al. PLoS Pathog. 2021 Jun 1;17(6):e1009596. doi: 10.1371/journal.ppat.1009596. eCollection 2021 Jun. PLoS Pathog. 2021. PMID: 34061905 Free PMC article.

3

The influence of viral RNA secondary structure on interactions with innate host cell defences.

Witteveldt J, Blundell R, Maarleveld JJ, McFadden N, Evans DJ, Simmonds P. Witteveldt J, et al. Among authors: simmonds p. Nucleic Acids Res. 2014 Mar;42(5):3314-29. doi: 10.1093/nar/gkt1291. Epub 2013 Dec 13. Nucleic Acids Res. 2014. PMID: 24335283 Free PMC article.

4

Viral meningitis: epidemiology and diagnosis.

Harvala H, Simmonds P. Harvala H, et al. Among authors: simmonds p. Lancet Infect Dis. 2016 Nov;16(11):1211-1212. doi: 10.1016/S1473-3099(16)30221-3. Epub 2016 Aug 12. Lancet Infect Dis. 2016. PMID: 27527750 No abstract available.

5

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus.

Ansari MA, Pedergnana V, L C Ip C, Magri A, Von Delft A, Bonsall D, Chaturvedi N, Bartha I, Smith D, Nicholson G, McVean G, Trebes A, Piazza P, Fellay J, Cooke G, Foster GR; STOP-HCV Consortium; Hudson E, McLauchlan J, Simmonds P, Bowden R, Klenerman P, Barnes E, Spencer CCA. Ansari MA, et al. Among authors: simmonds p. Nat Genet. 2017 May;49(5):666-673. doi: 10.1038/ng.3835. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394351 Free PMC article.

6

CpG and UpA dinucleotides in both coding and non-coding regions of echovirus 7 inhibit replication initiation post-entry.

Fros JJ, Dietrich I, Alshaikhahmed K, Passchier TC, Evans DJ, Simmonds P. Fros JJ, et al. Among authors: simmonds p. Elife. 2017 Sep 29;6:e29112. doi: 10.7554/eLife.29112. Elife. 2017. PMID: 28960178 Free PMC article.

7

The genomic underpinnings of eukaryotic virus taxonomy: creating a sequence-based framework for family-level virus classification.

Aiewsakun P, Simmonds P. Aiewsakun P, et al. Among authors: simmonds p. Microbiome. 2018 Feb 20;6(1):38. doi: 10.1186/s40168-018-0422-7. Microbiome. 2018. PMID: 29458427 Free PMC article.

8

Impact of virus subtype and host IFNL4 genotype on large-scale RNA structure formation in the genome of hepatitis C virus.

Simmonds P, Cuypers L, Irving WL, McLauchlan J, Cooke GS, Barnes E; STOP-HCV Consortium; Ansari MA. Simmonds P, et al. RNA. 2020 Nov;26(11):1541-1556. doi: 10.1261/rna.075465.120. Epub 2020 Aug 3. RNA. 2020. PMID: 32747607 Free PMC article.

9

Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7.

Goonawardane N, Nguyen D, Simmonds P. Goonawardane N, et al. Among authors: simmonds p. mSphere. 2021 Jan 6;6(1):e01138-20. doi: 10.1128/mSphere.01138-20. mSphere. 2021. PMID: 33408233 Free PMC article.

10

Comparison of CpG- and UpA-mediated restriction of RNA virus replication in mammalian and avian cells and investigation of potential ZAP-mediated shaping of host transcriptome compositions.

Odon V, Fiddaman SR, Smith AL, Simmonds P. Odon V, et al. Among authors: simmonds p. RNA. 2022 Aug;28(8):1089-1109. doi: 10.1261/rna.079102.122. Epub 2022 Jun 8. RNA. 2022. PMID: 35675984 Free PMC article.

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