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247 results

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Productive infection of primary human hepatocytes with SARS-CoV-2 induces antiviral and proinflammatory responses.
Heinen N, Khanal R, Westhoven S, Klöhn M, Herrmann ST, Herrmann M, Tuoc T, Ulmke PA, Nguyen HD, Nguyen HP, Steinmann E, Todt D, Brown RJP, Sharma AD, Pfaender S. Heinen N, et al. Among authors: sharma ad. Gut. 2023 Dec 12:gutjnl-2023-330961. doi: 10.1136/gutjnl-2023-330961. Online ahead of print. Gut. 2023. PMID: 38123990 Free article. No abstract available.
Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells.
Dai Z, Song G, Balakrishnan A, Yang T, Yuan Q, Möbus S, Weiss AC, Bentler M, Zhu J, Jiang X, Shen X, Bantel H, Jaeckel E, Kispert A, Vogel A, Saborowski A, Büning H, Manns M, Cantz T, Ott M, Sharma AD. Dai Z, et al. Among authors: sharma ad. Gut. 2020 Jun;69(6):1104-1115. doi: 10.1136/gutjnl-2019-318812. Epub 2019 Nov 25. Gut. 2020. PMID: 31767630 Free PMC article.
Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD. Yang T, et al. Among authors: sharma ad. J Hepatol. 2021 Dec;75(6):1420-1433. doi: 10.1016/j.jhep.2021.08.011. Epub 2021 Aug 25. J Hepatol. 2021. PMID: 34453962 Free article.
Corrigendum to 'Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model' [J Hepatol (2021) 1420-1433].
Yang T, Poenisch M, Khanal R, Hu Q, Dai Z, Li R, Song G, Yuan Q, Yao Q, Shen X, Taubert R, Engel B, Jaeckel E, Vogel A, Falk CS, Schambach A, Gerovska D, Araúzo-Bravo MJ, Vondran FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M, Sharma AD. Yang T, et al. Among authors: sharma ad. J Hepatol. 2022 Jul;77(1):270. doi: 10.1016/j.jhep.2022.03.023. Epub 2022 Apr 7. J Hepatol. 2022. PMID: 35397937 No abstract available.
Equal opportunity offer for all hepatocytes.
Dai Z, Ott M, Sharma AD. Dai Z, et al. Among authors: sharma ad. J Hepatol. 2020 Jul;73(1):6-8. doi: 10.1016/j.jhep.2020.03.038. Epub 2020 May 6. J Hepatol. 2020. PMID: 32386955 No abstract available.
Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis.
Song G, Pacher M, Balakrishnan A, Yuan Q, Tsay HC, Yang D, Reetz J, Brandes S, Dai Z, Pützer BM, Araúzo-Bravo MJ, Steinemann D, Luedde T, Schwabe RF, Manns MP, Schöler HR, Schambach A, Cantz T, Ott M, Sharma AD. Song G, et al. Among authors: sharma ad. Cell Stem Cell. 2016 Jun 2;18(6):797-808. doi: 10.1016/j.stem.2016.01.010. Epub 2016 Feb 25. Cell Stem Cell. 2016. PMID: 26923201 Free article.
Ex Vivo/In vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template.
Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J, Sharma AD, Büning H, Ott M. Krooss SA, et al. Among authors: sharma ad. iScience. 2020 Jan 24;23(1):100764. doi: 10.1016/j.isci.2019.100764. Epub 2019 Dec 12. iScience. 2020. PMID: 31887661 Free PMC article.
Corrigendum to: 'Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis' [J Hepatol (2019) 722-734].
Tsay HC, Yuan Q, Balakrishnan A, Kaiser M, Möbus S, Kozdrowska E, Farid M, Tegtmeyer PK, Borst K, Vondran FWR, Kalinke U, Kispert A, Manns MP, Ott M, Sharma AD. Tsay HC, et al. Among authors: sharma ad. J Hepatol. 2022 Jul;77(1):269. doi: 10.1016/j.jhep.2022.03.022. Epub 2022 Apr 6. J Hepatol. 2022. PMID: 35397938 No abstract available.
247 results